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Fig. 4 | BMC Genetics

Fig. 4

From: Evaluation of forensic DNA mixture evidence: protocol for evaluation, interpretation, and statistical calculations using the combined probability of inclusion

Fig. 4

A depiction of the vWA locus illustrating the application of R2. Threshold parameters in this example are: ST = 200 and AT = 50 RFU. Hence the obligate minor allele at 18 is above the ST and drop-out of its sister allele is unlikely. This locus is qualified for use in the CPI calculation. Under the assumption of two contributors there is one minor allele unconfirmed. Both the 15 and 19 peaks are below the stutter filter (SF) and hence could be all stutter or a composite of stutter and allele. This example illustrates the scenario where peaks in the stutter position fall below the SF. The partner to the 18 allele must be at one of the positions 15,16,18,19, or 20. Since the minor contributor genotype cannot be resolved with sufficient confidence, for this example the probability of inclusion is calculated as PI = (p 15 + p 16 + p 18 + p 19 + p 20)2

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