Table 3 Association between ABCB1 C3435T genotypes and breast cancer risk factors in Moroccan patients

BMI

60

 <22 kg/m²

17

11 (64.7)

4 (23.5)

2 (11.8)

0.36

 ≥22 kg/m²

43

19 (44.2)

16 (37.2)

8 (18.6)

Age of menarche (years)

60

 <13

16

9 (56.25)

4 (25.0)

3 (18.75)

0.71

 ≥13

44

21 (47.7)

16 (36.4)

7 (15.9)

Age of first pregnancy (years)

40

 <25

23

11 (47.8)

8 (34.8)

4 (17.4)

0.08

 ≥25

17

10 (58.8)

1 (5.9)

6 (35.3)

Number of pregnancies

60

 ≤1

30

14 (46.7)

12 (40.0)

4 (13.3)

0.51

 >1

30

16 (53.3)

8 (26.7)

6 (20.0)

Number of abortions

60

 ≤1

55

28 (50.9)

19 (34.5)

8 (14.5)

0.34

 >1

5

2 (40.0)

1 (20.0)

2 (40.0)

Oral contraceptives use

60

 Yes

35

18 (51.4)

10 (28.6)

7 (20.0)

0.56

 No

25

12 (48.0)

10 (40.0)

3 (12.0)

Family history of breast cancer

60

 Yes

29

14 (48.3)

8 (27.6)

7 (24.1)

0.29

 No

31

16 (51.6)

12 (38.7)

3 (9.7)

Age group (years)

60

 ≤40

34

20 (58.8)

10 (29.4)

4 (11.8)

0.25

 >40

26

10 (38.5)

10 (38.5)

6 (23.1)

Menopausal status

60

 Premenopausal

40

22 (55.0)

11 (27.5)

7 (17.5)

0.26

 Postmenopausal

20

8 (40.0)

9 (45.0)

3 (15.0)

Breastfeeding

60

 Yes

31

17 (54.8)

8 (25.8)

6 (19.4)

0.43

 No

29

13 (44.8)

12 (41.4)

4 (13.8)