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Table 3 Association between ABCB1 C3435T genotypes and breast cancer risk factors in Moroccan patients

From: Association between ABCB1 C3435T polymorphism and breast cancer risk: a Moroccan case-control study and meta-analysis

Variable Total C3435T polymorphism genotypes P value
CC (%) CT (%) TT (%)
BMI 60     
 <22 kg/m2 17 11 (64.7) 4 (23.5) 2 (11.8) 0.36
 ≥22 kg/m2 43 19 (44.2) 16 (37.2) 8 (18.6)
Age of menarche (years) 60     
 <13 16 9 (56.25) 4 (25.0) 3 (18.75) 0.71
 ≥13 44 21 (47.7) 16 (36.4) 7 (15.9)
Age of first pregnancy (years) 40     
 <25 23 11 (47.8) 8 (34.8) 4 (17.4) 0.08
 ≥25 17 10 (58.8) 1 (5.9) 6 (35.3)
Number of pregnancies 60     
 ≤1 30 14 (46.7) 12 (40.0) 4 (13.3) 0.51
 >1 30 16 (53.3) 8 (26.7) 6 (20.0)
Number of abortions 60     
 ≤1 55 28 (50.9) 19 (34.5) 8 (14.5) 0.34
 >1 5 2 (40.0) 1 (20.0) 2 (40.0)
Oral contraceptives use 60     
 Yes 35 18 (51.4) 10 (28.6) 7 (20.0) 0.56
 No 25 12 (48.0) 10 (40.0) 3 (12.0)
Family history of breast cancer 60     
 Yes 29 14 (48.3) 8 (27.6) 7 (24.1) 0.29
 No 31 16 (51.6) 12 (38.7) 3 (9.7)
Age group (years) 60     
 ≤40 34 20 (58.8) 10 (29.4) 4 (11.8) 0.25
 >40 26 10 (38.5) 10 (38.5) 6 (23.1)
Menopausal status 60     
 Premenopausal 40 22 (55.0) 11 (27.5) 7 (17.5) 0.26
 Postmenopausal 20 8 (40.0) 9 (45.0) 3 (15.0)
Breastfeeding 60     
 Yes 31 17 (54.8) 8 (25.8) 6 (19.4) 0.43
 No 29 13 (44.8) 12 (41.4) 4 (13.8)
  1. BMI body mass index, CC homozygous wild-type, CT heterozygous, TT homozygous mutant, % percentage