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Table 4 Association between ABCB1 C3435T genotypes and clinico-pathological characteristics of breast cancer in Moroccan patients

From: Association between ABCB1 C3435T polymorphism and breast cancer risk: a Moroccan case-control study and meta-analysis

Variable Total C3435T polymorphism genotypes P value
CC (%) CT (%) TT (%)
Histology 60     
 IDC 54 26 (48.1) 19 (35.2) 9 (16.7) 0.44
 ILC 3 1 (33.3) 1 (33.3) 1 (33.3)
 Others 3 3 (100.0) - -
Tumor size 60     
 T1 7 2 (28.6) 3 (42.9) 2 (28.6) 0.41
 T2 29 15 (51.7) 8 (27.6) 6 (20.7)
 T3 11 8 (72.7) 3 (27.3) -
 T4 13 5 (38.5) 6 (46.2) 2 (15.4)
SBR 60     
 I 3 2 (66.7) - 1 (33.3) 0.61
 II 45 23 (51.1) 16 (35.6) 6 (13.3)
 III 12 5 (41.7) 4 (33.3) 3 (25.0)
Node involvement 60     
 N- 25 13 (52.0) 7 (28.0) 5 (20.0) 0.78
 N+ 34 17 (50.0) 12 (35.2) 5 (14.7)
Progesterone receptors status 60     
 PR- 27 16 (59.3) 8 (29.6) 3 (11.1) 0.38
 PR+ 33 14 (42.4) 12 (36.4) 7 (21.2)
Estrogen receptors status 60     
 ER- 22 14 (63.6) 5 (22.7) 3 (13.6) 0.27
 ER+ 38 16 (42.1) 15 (39.5) 7 (18.4)
  1. CC homozygous wild-type, CT heterozygous, TT homozygous mutant, % percentage, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, SBR Scarff–Bloom–Richardson, ER estrogen receptor, PR progesterone receptor