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Table 4 Association between ABCB1 C3435T genotypes and clinico-pathological characteristics of breast cancer in Moroccan patients

From: Association between ABCB1 C3435T polymorphism and breast cancer risk: a Moroccan case-control study and meta-analysis

Variable

Total

C3435T polymorphism genotypes

P value

CC (%)

CT (%)

TT (%)

Histology

60

    

 IDC

54

26 (48.1)

19 (35.2)

9 (16.7)

0.44

 ILC

3

1 (33.3)

1 (33.3)

1 (33.3)

 Others

3

3 (100.0)

-

-

Tumor size

60

    

 T1

7

2 (28.6)

3 (42.9)

2 (28.6)

0.41

 T2

29

15 (51.7)

8 (27.6)

6 (20.7)

 T3

11

8 (72.7)

3 (27.3)

-

 T4

13

5 (38.5)

6 (46.2)

2 (15.4)

SBR

60

    

 I

3

2 (66.7)

-

1 (33.3)

0.61

 II

45

23 (51.1)

16 (35.6)

6 (13.3)

 III

12

5 (41.7)

4 (33.3)

3 (25.0)

Node involvement

60

    

 N-

25

13 (52.0)

7 (28.0)

5 (20.0)

0.78

 N+

34

17 (50.0)

12 (35.2)

5 (14.7)

Progesterone receptors status

60

    

 PR-

27

16 (59.3)

8 (29.6)

3 (11.1)

0.38

 PR+

33

14 (42.4)

12 (36.4)

7 (21.2)

Estrogen receptors status

60

    

 ER-

22

14 (63.6)

5 (22.7)

3 (13.6)

0.27

 ER+

38

16 (42.1)

15 (39.5)

7 (18.4)

  1. CC homozygous wild-type, CT heterozygous, TT homozygous mutant, % percentage, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, SBR Scarff–Bloom–Richardson, ER estrogen receptor, PR progesterone receptor