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Table 1 Top five diseases and bio functions of the Ingenuity® pathway analyses

From: Adrenal cortex expression quantitative trait loci in a German Holstein × Charolais cross

Category

p-value

Molecules

Molecular and Cellular Function

 Free Radical Scavenging

2.69E-02-9.18E-02

TF, EPAS1, NQO1, CYCS, XDH

 Cellular Compromise

2.69E-02-5.98E-02

VIM, NQO1, CYCS, XDH

 Cell Morphology

2.69E-02-9.04E-02

VIM, MGAT5, LHCGR, NQO1, CYCS, GDPD2, XDH

 Lipid Metabolism

2.69E-02-9.39E-02

VIM, EPAS1, NQO1, LHCGR, CYCS, XDH, CYP27A1, PHYH

 Small Molecule Biochemistry

2.69E-02-9.39E-02

VIM, LYVE1, GSTO1, SLC2A9, EPAS1, NQO1, LHCGR, CYCS, XDH, CYP27A1, PHYH, EXTL2

Diseases and Disorders

 Inflammatory Response

2.69E-02-9.39E-02

VIM, GSTO1, TF, MGAT5, EPAS1, NQO1, LHCGR, CYCS, XDH

 Neurological Disease

2.69E-02-9.39E-02

VIM, GSTO1, TF, MGAT5, LHCGR, NQO1, XDH, CYP27A1, PHYH

 Organismal Injury and Abnormalities

2.69E-02-9.48E-02

VIM, TF, PTP4A2, MGAT5, EPAS1, LHCGR, NQO1, XDH, PHYH

 Psychological Disorders

2.69E-02-8.3E-02

VIM, GSTO1, TF, NQO1, CYP27A1, PHYH

 Reproductive System Disease

2.69E-02-8.7E-02

TF, PTP4A2, LHCGR, PHYH

Physiological System Development and Function

 Reproductive System Development and Function

2.69E-02-9.39E-02

TF, PTP4A2, EPAS1, LHCGR

 Tissue Morphology

2.69E-02-9.39E-02

VIM, TF, EPAS1, LHCGR, NQO1, XDH, PHYH

 Embryonic Development

2.69E-02-7.84E-02

VIM, LYVE1, TF, PTP4A2, EPAS1, LHCGR, NQO1, GDPD2

 Cardiovascular System Development and Function

2.69E-02-8.7E-02

VIM, TF, MGAT5, EPAS1, CYCS, XDH

 Hematological System Development and Function

2.69E-02-9.39E-02

TF, MGAT5, EPAS1, NQO1, LHCGR, CYCS, XDH

  1. The top five molecular and cellular functions, diseases and disorders as well as physiological system development and functions are displayed, Benjamini-Hochberg adjusted p-values and the related genes