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Fig. 2 | BMC Genetics

Fig. 2

From: Genes of susceptibility to early neurodegenerative changes in the rat retina and brain: analysis by means of congenic strains

Fig. 2

Retinas of 3-month-old WAG a and OXYS b c rats. a Open chorioretinal vessels with a small amount of blood cells (white dotted arrows); the cellular prismatic pigment epithelium with prominent microvilli (white arrows). b The ganglion neuron nucleus with pyknosis (black arrow); hyperchromic oligodendrocyte with nuclear pyknosis in the layer of nerve fibers (dashed black arrow); stasis of blood cells in the intraretinal vessel (white dashed arrow); hyperchromic pyknomorphic radial glial cells (white arrows); hyperchromic pyknomorphic associative neurons (red arrows). c Stasis and sludge of the blood cells in the choroidal vessels (black dashed arrows); a pyknotic nucleus of an RPE cell (black arrows); disorientation and disaggregation of the outer segments of photoreceptors (asterisk); the photoreceptors containing a nucleus with pyknosis (white dotted arrows). Abbreviations: OPL, outer plexiform layer; INL, inner nuclear layer; IPL, the inner plexiform layer; ONL, outer nuclear layer; GL, ganglion cell layer, RPE, retinal pigment epithelium, Ch, choroid. The scale bar is 10 μm

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