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Table 1 Top 40 genes with the greatest difference in expression between ISIAH and WAG renal medulla

From: The gene-expression profile of renal medulla in ISIAH rats with inherited stress-induced arterial hypertension

Gene symbol

NCBI gene ID

Gene definition

log2 (fold_change) ISIAH/WAG

LOC102546948

102546948

uncharacterized LOC102546948

−5.73

Galnt13

311039

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)

−5.56

Pdilt

293544

protein disulfide isomerase-like, testis expressed

−5.17

LOC501110

501110

similar to Glutathione S-transferase A1 (GTH1) (HA subunit 1) (GST-epsilon) (GSTA1-1) (GST class-alpha)

−4.59

Slc10a2

29500

solute carrier family 10 (sodium/bile acid cotransporter), member 2

−4.40

Pcdh9

306091

protocadherin 9

−4.23

LOC100909561

100909561

nuclease-sensitive element-binding protein 1-like

−3.74

Car5a

54233

carbonic anhydrase 5a, mitochondrial

−3.74

LOC100361907

100361907

complement factor H-related protein B

−3.73

Sphkap

316561

SPHK1 interactor, AKAP domain containing

−3.65

LOC102552001

102552001

uncharacterized LOC102552001

−3.62

LOC102550987

102550987

uncharacterized LOC102550987

−3.57

Kcnj5

29713

potassium inwardly-rectifying channel, subfamily J, member 5

−3.23

Upk2

689093

uroplakin 2

3.12

LOC102555352

102555352

uncharacterized LOC102555352

3.13

LOC102551856

102551856

uncharacterized LOC102551856

3.21

Spta1

289257

spectrin, alpha, erythrocytic 1 (elliptocytosis 2)

3.28

LOC686967

686967

similar to olfactory receptor 1442

3.34

Acsm3 a

24763

acyl-CoA synthetase medium-chain family member 3

3.40

LOC100911960

100911960

UDP-glucuronosyltransferase 1-9-like

3.44

Thrsp

25357

thyroid hormone responsive

3.51

Sprr1a

499660

small proline-rich protein 1A

3.51

Hpgd

79242

hydroxyprostaglandin dehydrogenase 15 (NAD)

3.52

LOC102553290

102553290

collagen alpha-1(III) chain-like

3.62

Ly6al

362935

lymphocyte antigen 6 complex, locus A-like

3.65

Akr1b8

286921

aldo-keto reductase family 1, member B8

3.70

Shisa3

498356

shisa family member 3

3.83

Nefh

24587

neurofilament, heavy polypeptide

3.90

Tcerg1l

361669

transcription elongation regulator 1-like

4.09

Krt19

360626

keratin 19

4.18

Ephx2 a

65030

epoxide hydrolase 2, cytoplasmic

4.52

Ubd

29168

ubiquitin D

4.61

Resp18

50561

regulated endocrine-specific protein 18

4.65

Serpinb12

304692

serpin peptidase inhibitor, clade B (ovalbumin), member 12

5.38

Car3

54232

carbonic anhydrase 3

5.54

Fam111a

499322

family with sequence similarity 111, member A

5.86

LOC100362069

100362069

ribosomal protein L28-like

6.11

Gys2

25623

glycogen synthase 2

6.38

Stk32c

365381

serine/threonine kinase 32C

6.41

RGD1565131

498143

60S ribosomal protein L15-like

8.94

  1. aGenes are annotated in Rat Genome Database (http://rgd.mcw.edu/) as associated with hypertension. ISIAH and WAG – rat strains used in the study