Fig. 4
From: Haploid yeast cells undergo a reversible phenotypic switch associated with chromosome II copy number
The Lys+ phenotype is co-selected with resistance to GuHCl. An Isp+ (p1) isolate was passaged on either YEPD (upper line) or YEPD with 5mM GuHCl (middle line) five times; an Isp− isolate (m1) passaged on YEPD (lower line) is shown for comparison. Shown are five-fold serial dilutions starting with equal number of cells after 6 or 12 (indicated) days of incubation