From: MicroRNA-146a rs2910164 is associated with severe preeclampsia in Black South African women on HAART
 | GC/CC vs. GGa | ||
---|---|---|---|
PE Total | PE - | PE + | |
Age | 0.869 | 0.320 | 0.950 |
26.5 ± 1.11 (37) vs 26.8 ± 1.14 (36) | 24.3 ± 1.28 (18) vs 26.0 ± 1.08 (26) | 28.6 ± 1.68 (19) vs 28.8 ± 3.04 (10) | |
BMI | 0.675 | 0.225 | 0.390 |
(31.7 ± 1.25 (29) vs 32.6 ± 1.92 (17)) | (29.6 ± 1.66 (14) vs 34.4 ± 3.29 (8)) | 33.6 ± 1.77 (15) vs 31.1 ± 2.20 (9) | |
CD4 | 0.121 | - | 0.213 |
(414 ± 38.1 (20) vs 538 ± 65.0 (10)) | 408 ± 39.8 (19) vs 506 ± 63.4 (9) | ||
SYS BP | 0.866 | 0.875 | 0.671 |
160 ± 2.32 (45) vs 160 ± 3.91 (12) | 158 ± 3.26 (23) vs 157 ± 8.69 (5) | 161 ± 3.37 (22) vs 163 ± 3.04 (7) | |
DIA BP | 0.817 | 0.654 | 0.412 |
104 ± 1.57 (45) vs 105 ± 3.16 (12) | 102 ± 2.03 (23) vs 99.4 ± 6.04 (5) | 105 ± 2.43 (22) vs 108 ± 2.91 (7) | |
Severe PE (%) | 0.0497 | 0.364 | 0.017 |
14 (38) vs 14 (61) | 7 (39) vs 6 (46) | 7 (37) vs 8 (80) | |
EOPE (%) | 0.497 | 0.501 | 0.498 |
14 (38) vs 9 (39) | 5 (28) vs 4 (31) | 9 (47) vs 5 (50) | |
IL-2 | 0.201 | 0.240 | 0.885 |
262 ± 4.78 (10) vs 282 ± 13.1 (7) | 268 ± 6.83 (4) vs 279 ± 5.09 (3) | 258 ± 6.54 (6) vs 260 ± 7.54 (3) | |
IL-4 | 0.758 | 0.801 | 0.549 |
(247 ± 8.18 (10) vs 251 ± 5.29 (7)) | 261 ± 18.9 (4) vs 255 ± 7.34 (4) | 238 ± 4.12 (6) vs 244 ± 7.08 (3) | |
IL-6 | 0.095 | 0.534 | 0.334 |
139 ± 7.93 (10) vs 171 ± 15.5 (7) | 163 ± 14.5 (3) vs 181 ± 22.7 (4) | 128 ± 6.66 (7) vs 158 ± 22.3 (3) | |
IL-10 | 0.895 | 0.697 | 0.107 |
147 ± 70.3 (9) vs 133 ± 70.4 (6) | 273 ± 140 (4) vs 188 ± 147 (3) | 45.4 ± 15.8 (5) vs 78.5 ± 2.77 (3) | |
IL-17a | 0.758 | 0.475 | 0.511 |
1430 ± 313 (9) vs 1690 ± 728 (6) | 820 ± 32.1 (4) vs 750 ± 79.3 (4) | 1920 ± 466 (5) vs 3550 ± 1630 (2) | |
TNF-α | 0.920 | 0.418 | 0.316 |
186 ± 15.4 (11) vs 183 ± 25.2 (7) | 227 ± 25.4 (4) vs 179 ± 45.5 (4) | 164 ± 14.0 (7) vs 189 ± 16.9 (3) | |
IFN-γ | 0.315 | 0.507 | 0.668 |
206 ± 17.0 (11) vs 227 ± 11.2 (6) | 201 ± 50.4 (4) vs 240 ± 10.6 (4) | 208 ± 5.02 (7) vs 200 ± 12.6 (2) |