Table 6 Main transcription factors (TF) associated with genes overlapping with significant SNPs or regions and their biological process and literature evidences related to meat pH
TF | Group | Biological Process (GO) | Literature evidence |
|---|---|---|---|
PPARG | Single SNPs and Region 11 | Regulation of caspase activity | Lipid and glucose homeostasis [47] |
SRF | Region 2 | Muscle cell homeostasis | Actin cytoskeleton and contractile homeostasis [59] |
Stat3 | Single SNPs and Region 1 | Homeostatic process | Glucose Homeostasis [60] |
PPARG::RXRA | Single SNPs and Regions 1 and 3 | Homeostatic process | Lipid and glucose homeostasis [47] |
Arnt::Ahr | Single SNPs and Region 3 | Regulation of homeostatic process | Cellular homeostasis [61] |
STAT1 | Region 1 | Regulation of caspase activity | Cellular homeostasis [62] |
Nkx2-5 | Region 2 | Regulation of calcium ion transport via voltage-gated calcium channel activity | Homeostasis [49] |
HNF4A | Single SNPs and Region 3 | Homeostatic process | Lipid homeostasis [46] |