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Table 5 Results of GRM association test in bipolar disorder WTCCC case-control sample (WTCCC 20007)

From: Gain of power of the general regression model compared to Cochran-Armitage Trend tests: simulation study and application to bipolar disorder

A: Test for association

Chromosome

SNP id

Rsid

Position

GRM P-value

CAT_ADD P-value

2

SNP_A-1964333

rs7570682

104349699

4,26E-6

7,91E-7

2

SNP_A-1916900

rs11123306

115948251

4,77E-6

7,53E-7

2

SNP_A-2300074

rs1375144

115957416

8,18E-6

1,25E-6

3

SNP_A-2266670

rs4276227

32305690

2,16E-5

3,47E-6

6

SNP_A-4217035

rs6458307

42839093

3,38E-6

0,28

9

SNP_A-2106829

rs10982256

114340388

3,73E-5

6,59E-6

14

SNP_A-2284698

rs10134944

57188949

2,67E-6

1,91E-6

14

SNP_A-4304670

rs11622475

103578829

1,11E-5

2,17E-6

16

SNP_A-2248415

rs420259

23541527

3,37E-7

9.3E-4

16

SNP_A-2306762

rs1344484

51469800

6,81E-6

1,03E-6

20

SNP_A-1909934

rs3761218

3724175

9,96E-6

2,24E-5

B Test for genetic model

SNP id

rsid

β_ADD

ICβ_ADD (99%)

β_ADD P-value

β_DomDev

β_DomDev P-value

Genetic Model

SNP_A-2248415

rs420259

−0.33

−0.49

1.32

1.57E-7

0.35

5.56E-6

Recessive

  1. In bold: p < 5.0E-7
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