TY - JOUR AU - Mani, R. AU - St Onge, R. P. AU - Hartman, J. L. AU - Giaever, G. AU - Roth, F. P. PY - 2008 DA - 2008// TI - Defining genetic interaction JO - Proc Natl Acad Sci U S A VL - 105 UR - https://doi.org/10.1073/pnas.0712255105 DO - 10.1073/pnas.0712255105 ID - Mani2008 ER - TY - JOUR AU - Segrè, D. AU - Deluna, A. AU - Church, G. M. AU - Kishony, R. PY - 2005 DA - 2005// TI - Modular epistasis in yeast metabolism JO - Nat Genet VL - 37 ID - Segrè2005 ER - TY - JOUR AU - Charlesworth, B. PY - 1990 DA - 1990// TI - Mutation-selection balance and the evolutionary advantage of sex and recombination JO - Genet Res VL - 55 UR - https://doi.org/10.1017/S0016672300025532 DO - 10.1017/S0016672300025532 ID - Charlesworth1990 ER - TY - JOUR AU - Azevedo, R. B. AU - Lohaus, R. AU - Srinivasan, S. AU - Dang, K. K. AU - Burch, C. L. PY - 2006 DA - 2006// TI - Sexual reproduction selects for robustness and negative epistasis in artificial gene networks JO - Nature VL - 440 UR - https://doi.org/10.1038/nature04488 DO - 10.1038/nature04488 ID - Azevedo2006 ER - TY - JOUR AU - Rice, S. H. PY - 1998 DA - 1998// TI - The evolution of canalization and the breaking of von Baer’s laws: modeling the evolution of development with epistasis JO - Evolution VL - 52 UR - https://doi.org/10.2307/2411260 DO - 10.2307/2411260 ID - Rice1998 ER - TY - JOUR AU - Zhivotovsky, L. A. AU - Gavrilets, S. PY - 1992 DA - 1992// TI - Quantitative variability and multilocus polymorphism under epistatic selection JO - Theor Popul Biol VL - 42 UR - https://doi.org/10.1016/0040-5809(92)90015-L DO - 10.1016/0040-5809(92)90015-L ID - Zhivotovsky1992 ER - TY - JOUR AU - Presgraves, D. C. PY - 2007 DA - 2007// TI - Speciation Genetics: Epistasis, Conflict and the Origin of Species JO - Curr Biol VL - 17 UR - https://doi.org/10.1016/j.cub.2006.12.030 DO - 10.1016/j.cub.2006.12.030 ID - Presgraves2007 ER - TY - JOUR AU - Boone, C. AU - Bussey, H. AU - Andrews, B. J. PY - 2007 DA - 2007// TI - Exploring genetic interactions and networks with yeast JO - Nat Rev Genet VL - 8 UR - https://doi.org/10.1038/nrg2085 DO - 10.1038/nrg2085 ID - Boone2007 ER - TY - JOUR AU - Tong, A. H. AU - Lesage, G. AU - Bader, G. D. AU - Ding, H. AU - Xu, H. AU - Xin, X. PY - 2004 DA - 2004// TI - Global mapping of the yeast genetic interaction network JO - Science VL - 303 UR - https://doi.org/10.1126/science.1091317 DO - 10.1126/science.1091317 ID - Tong2004 ER - TY - JOUR AU - Lehner, B. AU - Crombie, C. AU - Tischler, J. AU - Fortunato, A. AU - Fraser, A. G. PY - 2006 DA - 2006// TI - Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways JO - Nat Genet VL - 38 UR - https://doi.org/10.1038/ng1844 DO - 10.1038/ng1844 ID - Lehner2006 ER - TY - JOUR AU - Byrne, A. B. AU - Weirauch, M. T. AU - Wong, V. AU - Koeva, M. AU - Dixon, S. J. AU - Stuart, J. M. PY - 2007 DA - 2007// TI - A global analysis of genetic interactions in Caenorhabditis elegans JO - J Biol VL - 6 UR - https://doi.org/10.1186/jbiol58 DO - 10.1186/jbiol58 ID - Byrne2007 ER - TY - JOUR AU - Collins, S. R. AU - Schuldiner, M. AU - Krogan, N. J. AU - Weissman, J. S. PY - 2006 DA - 2006// TI - A strategy for extracting and analyzing large-scale quantitative epistatic interaction data JO - Genome Biol VL - 7 UR - https://doi.org/10.1186/gb-2006-7-7-r63 DO - 10.1186/gb-2006-7-7-r63 ID - Collins2006 ER - TY - JOUR AU - Schuldiner, M. AU - Collins, S. R. AU - Thompson, N. J. AU - Denic, V. AU - Bhamidipati, A. AU - Punna, T. PY - 2005 DA - 2005// TI - Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile JO - Cell VL - 123 UR - https://doi.org/10.1016/j.cell.2005.08.031 DO - 10.1016/j.cell.2005.08.031 ID - Schuldiner2005 ER - TY - JOUR AU - Roguev, A. AU - Bandyopadhyay, S. AU - Zofall, M. AU - Zhang, K. AU - Fischer, T. AU - Collins, S. R. PY - 2008 DA - 2008// TI - Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast JO - Science VL - 322 UR - https://doi.org/10.1126/science.1162609 DO - 10.1126/science.1162609 ID - Roguev2008 ER - TY - JOUR AU - Butland, G. AU - Babu, M. AU - Díaz-Mejía, J. J. AU - Bohdana, F. AU - Phanse, S. AU - Gold, B. PY - 2008 DA - 2008// TI - eSGA: E. coli synthetic genetic array analysis JO - Nat Methods VL - 5 UR - https://doi.org/10.1038/nmeth.1239 DO - 10.1038/nmeth.1239 ID - Butland2008 ER - TY - JOUR AU - Bakal, C. AU - Linding, R. AU - Llense, F. AU - Heffern, E. AU - Martin-Blanco, E. AU - Pawson, T. PY - 2008 DA - 2008// TI - Phosphorylation networks regulating JNK activity in diverse genetic backgrounds JO - Science VL - 322 UR - https://doi.org/10.1126/science.1158739 DO - 10.1126/science.1158739 ID - Bakal2008 ER - TY - JOUR AU - Laufer, C. AU - Fischer, B. AU - Billmann, M. AU - Huber, W. AU - Boutros, M. PY - 2013 DA - 2013// TI - Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping JO - Nat Methods VL - 10 UR - https://doi.org/10.1038/nmeth.2436 DO - 10.1038/nmeth.2436 ID - Laufer2013 ER - TY - JOUR AU - Roguev, A. AU - Talbot, D. AU - Negri, G. L. AU - Shales, M. AU - Cagney, G. AU - Bandyopadhyay, S. PY - 2013 DA - 2013// TI - Quantitative genetic-interaction mapping in mammalian cells JO - Nat Methods VL - 10 UR - https://doi.org/10.1038/nmeth.2398 DO - 10.1038/nmeth.2398 ID - Roguev2013 ER - TY - JOUR AU - Fischer, B. AU - Sandmann, T. AU - Horn, T. AU - Billmann, M. AU - Chaudhary, V. AU - Huber, W. PY - 2015 DA - 2015// TI - A map of directional genetic interactions in a metazoan cell JO - Elife VL - 4 ID - Fischer2015 ER - TY - STD TI - Ahringer J. ed. Reverse genetics. 2006 WormBook, ed. The C. elegans Research Community, WormBook, doi: 10.1895/wormbook.1.47.1, http://www.wormbook.org. UR - http://www.wormbook.org ID - ref20 ER - TY - JOUR AU - Jung, S. K. AU - Aleman-Meza, B. AU - Riepe, C. AU - Zhong, W. PY - 2014 DA - 2014// TI - QuantWorm: a comprehensive software package for Caenorhabditis elegans phenotypic assays JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0084830 DO - 10.1371/journal.pone.0084830 ID - Jung2014 ER - TY - JOUR AU - Labocha, M. K. AU - Jung, S. K. AU - Aleman-Meza, B. AU - Liu, Z. AU - Zhong, W. PY - 2015 DA - 2015// TI - WormGender - Open-Source Software for Automatic Caenorhabditis elegans Sex Ratio Measurement JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0139724 DO - 10.1371/journal.pone.0139724 ID - Labocha2015 ER - TY - JOUR AU - Baryshnikova, A. AU - Costanzo, M. AU - Myers, C. L. AU - Andrews, B. AU - Boone, C. PY - 2013 DA - 2013// TI - Genetic interaction networks: toward an understanding of heritability JO - Annu Rev Genomics Hum Genet VL - 14 UR - https://doi.org/10.1146/annurev-genom-082509-141730 DO - 10.1146/annurev-genom-082509-141730 ID - Baryshnikova2013 ER - TY - JOUR AU - Babu, M. AU - Arnold, R. AU - Bundalovic-Torma, C. AU - Gagarinova, A. AU - Wong, K. S. AU - Kumar, A. PY - 2014 DA - 2014// TI - Quantitative genome-wide genetic interaction screens reveal global epistatic relationships of protein complexes in Escherichia coli JO - PLoS Genet VL - 10 UR - https://doi.org/10.1371/journal.pgen.1004120 DO - 10.1371/journal.pgen.1004120 ID - Babu2014 ER - TY - BOOK AU - Sokal, R. R. AU - Rohlf, F. J. PY - 1995 DA - 1995// TI - Biometry: the principles and practice of statistics in biological research PB - Freeman CY - San Francisco ID - Sokal1995 ER - TY - JOUR AU - Benjamini, Y. AU - Hochberg, Y. PY - 1995 DA - 1995// TI - Controlling the false discovery rate: a practical and powerful approach to multiple testing JO - J R Stat Soc B VL - 57 ID - Benjamini1995 ER - TY - JOUR AU - Karypis, G. AU - Kumar, V. A. PY - 1999 DA - 1999// TI - Fast and Highly Quality Multilevel Scheme for Partitioning Irregular Graphs JO - SIAM J Sci Comput VL - 20 UR - https://doi.org/10.1137/S1064827595287997 DO - 10.1137/S1064827595287997 ID - Karypis1999 ER - TY - STD TI - Meyer BJ. X-Chromosome dosage compensation. 2005. WormBook, ed. The C. elegans Research Community, WormBook, doi:10.1895/wormbook.1.8.1, http://www.wormbook.org. UR - http://www.wormbook.org ID - ref28 ER - TY - JOUR AU - Boulton, S. J. AU - Martin, J. S. AU - Polanowska, J. AU - Hill, D. E. AU - Gartner, A. AU - Vidal, M. PY - 2004 DA - 2004// TI - BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans JO - Curr Biol VL - 14 UR - https://doi.org/10.1016/j.cub.2003.11.029 DO - 10.1016/j.cub.2003.11.029 ID - Boulton2004 ER - TY - JOUR AU - Miki, Y. AU - Swensen, J. AU - Shattuck-Eidens, D. AU - Futreal, P. A. AU - Harshman, K. AU - Tavtigian, S. PY - 1994 DA - 1994// TI - A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 JO - Science VL - 266 UR - https://doi.org/10.1126/science.7545954 DO - 10.1126/science.7545954 ID - Miki1994 ER - TY - JOUR AU - Baer, R. AU - Ludwig, T. PY - 2002 DA - 2002// TI - The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity JO - Curr Opin Genet Dev VL - 12 UR - https://doi.org/10.1016/S0959-437X(01)00269-6 DO - 10.1016/S0959-437X(01)00269-6 ID - Baer2002 ER - TY - JOUR AU - Karppinen, S. M. AU - Heikkinen, K. AU - Rapakko, K. AU - Winqvist, R. PY - 2004 DA - 2004// TI - Mutation screening of the BARD1 gene: evidence for involvement of the Cys557Ser allele in hereditary susceptibility to breast cancer JO - J Med Genet VL - 41 UR - https://doi.org/10.1136/jmg.2004.020669 DO - 10.1136/jmg.2004.020669 ID - Karppinen2004 ER - TY - JOUR AU - Cousineau, I. AU - Abaji, C. AU - Belmaaza, A. PY - 2005 DA - 2005// TI - BRCA1 regulates RAD51 function in response to DNA damage and suppresses spontaneous sister chromatid replication slippage: implications for sister chromatid cohesion, genome stability, and carcinogenesis JO - Cancer Res VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-05-2156 DO - 10.1158/0008-5472.CAN-05-2156 ID - Cousineau2005 ER - TY - JOUR AU - Scully, R. AU - Chen, J. AU - Plug, A. AU - Xiao, Y. AU - Weaver, D. AU - Feunteun, J. PY - 1997 DA - 1997// TI - Association of BRCA1 with Rad51 in mitotic and meiotic cells JO - Cell VL - 88 UR - https://doi.org/10.1016/S0092-8674(00)81847-4 DO - 10.1016/S0092-8674(00)81847-4 ID - Scully1997 ER - TY - STD TI - Gudmundsdottir  K, Ashworth A. The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene. 2006;25:5864–74. ID - ref35 ER - TY - JOUR AU - Watkins, J. AU - Weekes, D. AU - Shah, V. AU - Gazinska, P. AU - Joshi, S. AU - Sidhu, B. PY - 2015 DA - 2015// TI - Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers JO - Cancer Discov VL - 5 UR - https://doi.org/10.1158/2159-8290.CD-14-1092 DO - 10.1158/2159-8290.CD-14-1092 ID - Watkins2015 ER - TY - JOUR AU - Salz, T. AU - Deng, C. AU - Pampo, C. AU - Siemann, D. AU - Qiu, Y. AU - Brown, K. PY - 2015 DA - 2015// TI - Histone Methyltransferase hSETD1A Is a Novel Regulator of Metastasis in Breast Cancer JO - Mol Cancer Res VL - 13 UR - https://doi.org/10.1158/1541-7786.MCR-14-0389 DO - 10.1158/1541-7786.MCR-14-0389 ID - Salz2015 ER - TY - JOUR AU - Fusco, N. AU - Geyer, F. C. AU - De Filippo, M. R. AU - Martelotto, L. G. AU - Ng, C. K. AU - Piscuoglio, S. PY - 2016 DA - 2016// TI - Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer JO - Mod Pathol VL - 29 UR - https://doi.org/10.1038/modpathol.2016.134 DO - 10.1038/modpathol.2016.134 ID - Fusco2016 ER - TY - JOUR AU - Manso, L. AU - Mourón, S. AU - Tress, M. AU - Gómez-López, G. AU - Morente, M. AU - Ciruelos, E. PY - 2016 DA - 2016// TI - Analysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal Resistance JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0155840 DO - 10.1371/journal.pone.0155840 ID - Manso2016 ER - TY - JOUR AU - Ansari, K. I. AU - Hussain, I. AU - Kasiri, S. AU - Mandal, S. S. PY - 2012 DA - 2012// TI - HOXC10 is overexpressed in breast cancer and transcriptionally regulated by estrogen via involvement of histone methylases MLL3 and MLL4 JO - J Mol Endocrinol VL - 48 UR - https://doi.org/10.1530/JME-11-0078 DO - 10.1530/JME-11-0078 ID - Ansari2012 ER - TY - JOUR AU - Rabello Ddo, A. AU - Moura, C. A. AU - Andrade, R. V. AU - Motoyama, A. B. AU - Silva, F. P. PY - 2013 DA - 2013// TI - Altered expression of MLL methyltransferase family genes in breast cancer JO - Int J Oncol VL - 43 ID - Rabello Ddo2013 ER - TY - JOUR AU - Kamath, R. S. AU - Fraser, A. G. AU - Dong, Y. AU - Poulin, G. AU - Durbin, R. AU - Gotta, M. PY - 2003 DA - 2003// TI - Systematic functional analysis of the Caenorhabditis elegans genome using RNAi JO - Nature VL - 421 UR - https://doi.org/10.1038/nature01278 DO - 10.1038/nature01278 ID - Kamath2003 ER - TY - JOUR AU - Rual, J. F. AU - Ceron, J. AU - Koreth, J. AU - Hao, T. AU - Nicot, A. S. AU - Hirozane-Kishikawa, T. PY - 2004 DA - 2004// TI - Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library JO - Genome Res VL - 14 UR - https://doi.org/10.1101/gr.2505604 DO - 10.1101/gr.2505604 ID - Rual2004 ER - TY - STD TI - Stiernagle T. Maintenance of C. elegans. 2006. WormBook. ed. The C. elegans Research Community, WormBook, doi:10.1895/wormbook.1.101.1, http://www.wormbook.org. UR - http://www.wormbook.org ID - ref44 ER - TY - JOUR AU - Venegas, V. AU - Zhou, Z. PY - 2007 DA - 2007// TI - Two alternative mechanisms that regulate the presentation of apoptotic cell engulfment signal in Caenorhabditis elegans JO - Mol Biol Cell VL - 18 UR - https://doi.org/10.1091/mbc.E07-02-0138 DO - 10.1091/mbc.E07-02-0138 ID - Venegas2007 ER - TY - BOOK PY - 2016 DA - 2016// TI - R: A language and environment for statistical computing PB - R Foundation for Statistical Computing CY - Vienna ID - ref46 ER -