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Table 2 The occurrence of adverse drug events according to the grouped genotypes of ADRB2

From: Association between ß2-adrenergic receptor gene polymorphisms and adverse events of ritodrine in the treatment of preterm labor: a prospective observational study

Gene Polymorphisms

Minor Allele Frequency

Grouped Genotypes

Number of Patients

Patients with ADE (#)

Patients without ADE (#)

Odds Ratio (95% Confidence Interval)

P-value

rs1042713 A > G Arg16Gly

0.47

AA, AG

145

29

116

1

.167

GG

41

4

37

0.432 (0.143–1.311)

rs1042714 C > G Gln27Glu

0.10

CC

151

25

126

1

.461

CG, GG

35

8

27

1.493 (0.608–3.666)

rs1042717 G > A Leu84Leu

0.36

GG, GA

162

33

129

1

.009

AA

24

0

24

0.843a (0.787–0.903)

rs1042718 C > A Arg175Arg

0.36

CC, CA

162

33

129

1

.009

AA

24

0

24

0.843a (0.787–0.903)

rs1042719 G > C Gly351Gly

0.46

GG, GC

146

31

115

1

.018

CC

40

2

38

0.195 (0.045–0.854)

  1. aData were expressed as relative risks
  2. ADE Adverse Drug Event