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Table 2 The occurrence of adverse drug events according to the grouped genotypes of ADRB2

From: Association between ß2-adrenergic receptor gene polymorphisms and adverse events of ritodrine in the treatment of preterm labor: a prospective observational study

Gene Polymorphisms Minor Allele Frequency Grouped Genotypes Number of Patients Patients with ADE (#) Patients without ADE (#) Odds Ratio (95% Confidence Interval) P-value
rs1042713 A > G Arg16Gly 0.47 AA, AG 145 29 116 1 .167
GG 41 4 37 0.432 (0.143–1.311)
rs1042714 C > G Gln27Glu 0.10 CC 151 25 126 1 .461
CG, GG 35 8 27 1.493 (0.608–3.666)
rs1042717 G > A Leu84Leu 0.36 GG, GA 162 33 129 1 .009
AA 24 0 24 0.843a (0.787–0.903)
rs1042718 C > A Arg175Arg 0.36 CC, CA 162 33 129 1 .009
AA 24 0 24 0.843a (0.787–0.903)
rs1042719 G > C Gly351Gly 0.46 GG, GC 146 31 115 1 .018
CC 40 2 38 0.195 (0.045–0.854)
  1. aData were expressed as relative risks
  2. ADE Adverse Drug Event