Study |
n
|
\(\bar \lambda \)
|
\(\bar \lambda _{10\%}\)
|
λ
′
|
λ
f;m;c′ |
\(\bar {G}\)
|
\(R^{2}_{\mathrm {t}}\)
|
|---|
HapMap | 129 | 1.288 (0.074) | 1.295 (0.051) | 1.297 | - | 0.006 | 0.152 |
SFS1 | 129 | 1.284 (0.087) | 1.293 (0.051) | 1.294 | 1.295 | 0.007 | 0.153 |
SFS2 | 999 | 1.306 (0.050) | 1.313 (0.020) | 1.314 | 1.299 | 0.001 | 0.143 |
Sorbs | 977 | 1.410 (0.135) | 1.448 (0.071) | 1.449 | - | 0.001 | 0.100 |
SFS3 | 999 | 2.006 (0.139) | 2.022 (0.083) | 2.021 | 2.002 | 0.002 | 0.044 |
- Variance inflation and related measures are compared between the data sets HapMap, SFS1 (synthetic family study 1), SFS2, Sorbs and SFS3 assuming \(R^{2}_{\mathrm {h}}=0.9\). Provided are the sample size n, average inflation \(\bar \lambda \) of all SNPs, average inflation \(\bar \lambda _{10\%}\) estimated for SNPs with minor allele frequencies > 10%, expected (theoretical) inflation λ
′ obtained from estimated relationships, expected inflation λ
f;m;c′ obtained from true relationships (synthetic family studies only), mean relatedness \(\bar {G}\) and heritability \(R^{2}_{\mathrm {t}}\)corresponding to inflation λt′=1.05. Standard deviations are given in parentheses
