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Table 1 Demographic characteristics of AA-DHS participants, by presence/absence of CAC

From: Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

Variables CAC 130 HU <10 (N = 346) CAC 130 HU ≥10 (N = 345) ALL (N = 691) P-value
Mean SD Median Mean SD Median Mean SD Median
Age (years) 52.8 8.7 52.0 59.8 9.0 60.0 56.3 9.6 56.0 <0.0001
Female (%) 66.5 53.6 60.1 0.0006
African Ancestry proportion (%) 76.4 14.9 78.9 73.8 16.0 76.4 75.1 15.5 78.0 0.05
Diabetes duration (years) 8.4 6.1 7.0 12.2 9.3 10.0 10.3 8.1 8.0 <0.0001
HbA1c (%) 8.3 2.3 7.8 8.1 1.9 7.6 8.2 2.1 7.7 0.94
C-reactive protein (mg/dl) 1.0 1.5 0.5 0.9 1.3 0.4 0.9 1.4 0.5 0.27
Glucose (mg/dl) 154.7 68.8 138.0 148.9 67.1 132.0 151.7 68.0 136.0 0.19
Low density lipoprotein cholesterol (mg/dl) 108.5 37.4 106.0 107.1 36.6 103.0 107.8 36.9 105.0 0.46
High density lipoprotein cholesterol (mg/dl) 48.2 14.4 46.0 47.8 14.4 45.0 48.0 14.4 46.0 0.51
Triglycerides (mg/dl) 128.2 112.0 104.0 128.2 130.4 100.0 128.2 121.5 102.0 0.66
Body Mass Index (kg/m2) 35.9 8.6 34.6 34.4 8.2 32.9 35.1 8.4 33.7 0.02
CAC 90 (Hounsfield unit) 8.8 16.1 1.5 1212.0 1810.9 442.0 609.4 1413.3 44.0 NA
CAC 130 (Hounsfield unit) 0.8 1.8 0.0 445.1 646.1 190.5 222.6 507.5 9.5 NA
ACE inhibitor use (%) 46.8 51.3 49.1 0.25
Current smoker (%) 20.3 25.2 22.8 0.007
Past smoker (%) 31.7 40.2 36.0 0.001
Hypertension (%) 78.0 89.1 83.6 0.0001
Lipid-lowering medication (%) 39.5 53.4 46.4 0.0004