Maternal variant in the upstream of FOXP3 gene on the X chromosome is associated with recurrent infertility in Japanese Black cattle

Table 1 SNPs associated with infertility in repeat-breeding Japanese Black heifers that failed to conceive by ET

SNP_ID	Chr	Position	Minor allele	Minor allele frequency in case	Minor allele frequency in control	Major allele	OR>^a	P	QTL^b_No.
ARS-BFGL-NGS-67406	X	8,602,946	A	0.50	0.08	G	11.53	5.35E-08	QTL_1
ARS-BFGL-NGS-42972	X	91,098,633	T	0.50	0.06	A	16.00	2.51E-08	QTL_2
ARS-BFGL-NGS-16377	X	92,216,380	C	0.52	0.07	G	15.38	3.86E-09	QTL_2
Hapmap48284-BTA-30349	X	92,260,895	G	0.52	0.07	A	15.38	3.86E-09	QTL_2
Hapmap53025-rs29010426	X	92,342,010	A	0.52	0.07	G	15.38	3.86E-09	QTL_2
BTA-30350-no-rs	X	92,373,745	G	0.52	0.07	A	15.38	3.86E-09	QTL_2
Hapmap53698-rs29016346	X	92,552,271	G	0.52	0.05	A	18.54	6.79E-10	QTL_2
ARS-BFGL-NGS-68512	X	104,393,600	G	0.62	0.10	A	14.26	1.57E-08	QTL_3
ARS-BFGL-NGS-36429	X	106,841,261	C	0.52	0.08	A	12.71	3.31E-08	QTL_4
ARS-BFGL-NGS-55906	X	106,901,051	A	0.52	0.07	G	14.87	1.15E-09	QTL_4
ARS-BFGL-NGS-109515	X	106,934,611	G	0.52	0.07	A	14.87	1.15E-09	QTL_4
ARS-BFGL-NGS-16664	X	108,144,345	A	0.72	0.24	G	8.24	5.16E-07	QTL_5
Hapmap34819-BES10_Contig519_871	X	108,731,811	A	0.88	0.32	G	15.83	2.73E-08	QTL_6

ISSN: 2730-6844