Table 6 Top ten targeter miRNAs for Rhesus monkey (that are connected with maximum number of gene-modules and that target maximum number genes from the connected modules) with information of their maximum number of targeted genes as well as gene-modules, and verified information of them
Sl. No. | MiRNAs | Number o connected gene-modules | Number of targeted genes | Name of the connected gene-modules (number of targeted genes in the modules) | Disease and Disease-verified information of miRNAs | Status of miRNAs |
|---|---|---|---|---|---|---|
1 | mml-miR-338-5p | 2 | 33 | Blue (6), Turquoise (27). | An auto immune disease like SIV [52] | Known |
2 | mml-miR-218 | 2 | 25 | Blue (6), Turquoise (19). | Huntintong’s Disease [53] | Known |
3 | mml-miR-768-3p | 2 | 25 | Blue (9), Turquoise (16). | Unknown | |
4 | mml-miR-495 | 2 | 24 | Blue (10), Turquoise (14). | Age mediated skeletal muscle contamination [54] | Known |
5 | mml-miR-203 | 2 | 24 | Blue (6), Turquoise (18). | Enhances Coxsackievirus B3 replication [55] | Known |
6 | mml-miR-561 | 2 | 24 | Blue (11), Turquoise (13). | Unknown | |
7 | mml-miR-590-3p | 2 | 23 | Blue (6), Turquoise (17). | Neuro inflammation Disorder [56] | Known |
8 | mml-miR-596 | 2 | 23 | Blue (2), Turquoise (21). | Schizophernia [57] | Known |
9 | mml-miR-548p | 2 | 22 | Blue (11), Turquoise (11). | monkey hippocampus effected [58]. | Known |
10 | mml-miR-524-5p | 2 | 22 | Blue (8), Turquoise (14). | Amyotrophic lateral sclerosis [59]. | Known |