An integrated and comparative approach towards identification, characterization and functional annotation of candidate genes for drought tolerance in sorghum (Sorghum bicolor (L.) Moench)

Table 3 Description of the top ten interpro-domains in decreasing order of frequency

Interpro-domain	Accession^a	F, P^b	Functional description	References
DnaJ domain	IPR001623	22, 6.4	Acts as protein chaperon; cooperation of Hsp40 with Hsp70 and endosomal trafficking^c	[58, 59]
Gamma thionin	IPR008176	18, 5.3	Plant defensins induced in response to drought	[82]
Ribosomal protein L29e	IPR002673	17, 5	Forms part of the 60S ribosomal subunit, structural constituent of ribosome^d	[83]
Zinc finger, CCHC-type	IPR001878	17, 5	Drought stress response in plants	[57]
DUF4281^e	IPR025461	16, 4.7	Protein domain functionally uncharacterised, found both in prokaryotes and eukaryotes	[84]
RNA recognition^f	IPR000504	16, 4.7	Expression of EgRBP42 transcript under drought stress	[85]
Cytochrome c oxidase, subunit VIIa	IPR003177	14, 4.1	Catalyses the reduction of oxygen to water in the inner mitochondrial membrane forming the functional core of the enzyme complex^g	[86]
Oligopeptide transporter family^h	IPR000109	14, 4.1	Showing an enhanced response in 35S:ABF3 plants that may contributing to drought-tolerance	[87]
Peptidase S10, serine carboxypeptidase	IPR018202	13, 3.8	Protein recognition and binding, serine carboxypeptidase-like gene OsBISCPL1 in rice is involved in regulation of defence responses	[88]
CBS domain	IPR000644	12, 3.5	Transcript levels of CBS domain containing proteins are altered in response to drought	[89]

Key to legend: ^aInterpro accession; ^bFrequency of occurrence, %; ^cIntracellular; ^dinvolve in translation and ribosome biogenesis; ^eProtein length range between 147 and 232 amino acids with known two functionally important conserved residues (W and P); ^fmotif domain; ^gtransferring the electrons from cytochrome c via its binuclear copper A centre to the bimetallic centre of the catalytic subunit 1; ^hProton-dependent

ISSN: 2730-6844