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Table 2 Association of ASPN D repeat and CILP rs2073711 polymorphism with hand OA

From: Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis

ASPN D15 & CILP rs2073711 N (casesa) OR (95% CI)b Stratified by occupation
Dentists / Teachers
OR (95% CI)
Stratified by variation in dental tasks (dentists only) - Low variation
OR (95% CI)
No D15 & CC + CT 300 (54) 1.0 1.0 1.0
At least one D15 or TT 224 (53) 1.43 (0.92–2-23) 2.48 (1.27–4.85), p = 0.008c/ 0.91 (0.50–1.67), p = 0.77 3.00 (1.35–6.66), p = 0.007d
  1. Logistic regression analysis; CI, confidence interval; OR, odds ratio
  2. aSymmetrical OA of grade 2 or more in at least two joints pairs
  3. bAdjusted for age (years) and occupation
  4. cBonferroni corrected p = 0.04
  5. dBonferroni corrected p = 0.035