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Fig. 1 | BMC Genetics

Fig. 1

From: Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies

Fig. 1

Impact of the balance between training vs. test data on power and type I error of the GRS-interaction-training approach. Scenarios with predominant interaction effects (a) and predominant marginal genetic effects (b). Balance training vs. test data increases from 19:1 to 1:19, scenarios with 6 risk SNPs that interact with the environmental exposure and 6, 50, 100 and 200 additional noise SNPs that are not associated with the outcome (N = 3000 observations and 1000 replications)

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