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Fig. 3 | BMC Genetics

Fig. 3

From: High resolution melting curve analysis targeting the HBB gene mutational hot-spot offers a reliable screening approach for all common as well as most of the rare beta-globin gene mutations in Bangladesh

Fig. 3

HRM curves patterns for the compound heterozygous mutations. a The normalized and temperature shifted difference curves for the compound heterozygous mutations c.47G > A plus c.79G > A, c.79G > A plus c.92G > C, c.46delT plus c.79G > A, c.27_28insG plus c.79G > A, c.79G > A plus c.92 + 5G > C, c.92G > C plus c.92 + 5G > C and wild type alleles. b The normalized and temperature shifted difference curves for the rare compound heterozygous mutations c.33C > A plus c.51delC and wild type allele

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