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Table 1 Relationship between albuminuria and genotype for genetic markers on chromosomes 2 and 10

From: Genetic loci for resistance to podocyte injury caused by the tensin2 gene deficiency in mice

Chromosome Marker Position (cM) χ2 (P) Student-T (P)c
Min/Maxa 50%b 40%b 30%b Min/Max 50% 40% 30%
2 D2Mit398 61.76 0.19 0.062 0.052 0.20 0.48 0.47 0.40 0.31
2 rs214164633 65.66 0.16 0.080 0.075 0.20 0.26 0.25 0.24 0.18
2 rs234188972 70.98 0.18 0.067 0.062 0.24 0.14 0.16 0.14 0.10
2 rs247793542 75.41 0.64 0.36 0.30 0.84 0.25 0.23 0.26 0.24
2 rs228447345 81.91 0.65 0.28 0.44 1 0.42 0.45 0.49 0.49
10 D10Mit298 2.78 0.58 0.42 0.60 0.48 0.43 0.47 0.36 0.29
10 D10Mit3 16.53 0.010 0.053 0.086 0.04 0.0099 0.0084 0.012 0.013
10 D10Mit197 35 0.049 0.059 0.059 0.10 0.0078 0.011 0.012 0.014
10 rs259766385 40.66 0.0022 0.0039 0.0068 0.0065 0.00038 0.00098 0.00074 0.00061
10 rs239646663 43.64 0.0043 0.0099 0.0040 0.019 0.00053 0.00076 0.0010 0.0015
10 D10Mit233 61.58 0.054 0.092 0.042 0.079 0.14 0.17 0.20 0.15
  1. aThe N2 mice with urinary albumin excretion larger than 3.1 g/gCr, the minimum value in FVB-Tns2nph mice, were defined as the FVB type (affected) and the N2 mice with urinary albumin excretion less than 0.7 g/gCr, the maximum value in B6- Tns2nph mice, were defined as the B6 type (not affected)
  2. bThe upper X% and lower X% of N2 mice in urinary albumin excretion were defined as the FVB type (affected) and the B6 type (not affected), respectively
  3. cUrinary albumin excretion in N2 mice was compared between those with B6/FVB and FVB/FVB genotypes at the genetic markers