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Table 2 Relationship between albuminuria and combined genotypes of chromosomes 2 and 10 (rs259766385)

From: Genetic loci for resistance to podocyte injury caused by the tensin2 gene deficiency in mice

Chromosome

Marker

Position (cM)

χ2 (P)

Student-T (P)c

Min/Maxa

50%b

40%b

30%b

Min/Max

50%

40%

30%

2

D2Mit398

61.76

0.003

0.0019

0.0049

0.014

0.055

0.078

0.075

0.027

2

rs214164633

65.66

0.0013

0.0012

0.0027

0.046

0.0016

0.0045

0.0028

0.0010

2

rs234188972

70.98

0.0013

0.00090

0.0032

0.0097

0.00021

0.0015

0.00083

0.00025

2

rs247793542

75.41

0.0063

0.0054

0.012

0.024

0.0020

0.0070

0.0042

0.0013

2

rs228447345

81.91

0.0039

0.0021

0.012

0.10

0.0089

0.028

0.025

0.015

  1. aThe N2 mice with urinary albumin excretion larger than 3.1 g/gCr, the minimum value in FVB-Tns2nph mice, were defined as the FVB type (affected) and the N2 mice with urinary albumin excretion less than 0.7 g/gCr, the maximum value in B6- Tns2nph mice, were defined as the B6 type (not affected)
  2. bThe upper X% and lower X% of N2 mice in urinary albumin excretion were defined as the FVB type (affected) and the B6 type (not affected), respectively
  3. cUrinary albumin excretion in the homogeneic genotype, in which both markers were FVB/FVB genotype, were compared with those in the heterogeneic genotype, in which at least one of the markers was B6/FVB genotype