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Table 3 Genes with (anti-)correlations between telomere length and gene expression listed in TelNet

From: TelNet - a database for human and yeast genes involved in telomere maintenance

Gene Rho p-value (Rho) log2 expr. Ratio p-value (expr.) TM information from TelNet TelNet score
PRPS2 0.25 4.7E-04 0.21 4.4E-01 Predicted from budding yeast homologue 1
GATA3 0.23 1.1E-03 −0.26 3.6E-01 Predicted from budding yeast homologue 1
ARL4D 0.22 1.8E-03 −1.02 8.6E-04 Predicted from budding yeast homologue 1
PDK3 0.22 2.4E-03 0.21 4.5E-01 Predicted from budding yeast homologue 1
FAM58A 0.20 4.2E-03 0.35 2.3E-01 Predicted from budding yeast homologue 1
MRPL34 0.20 5.4E-03 −0.25 3.8E-01 Predicted from budding yeast homologue 1
TSPYL5 0.19 7.7E-03 −0.63 3.5E-02 Predicted from budding yeast homologue 1
SUMO3 0.19 7.8E-03 0.16 5.4E-01 Validated in human 6
GIGYF2 −0.19 6.6E-03 −0.08 7.2E-01 Human screen for telomere shortening 2
PPM1D −0.20 5.9E-03 −0.30 2.9E-01 Predicted from budding yeast homologue 1
CTNNA1 −0.21 3.6E-03 −0.14 5.9E-01 Human screen for telomere shortening 2
ERCC5 −0.21 3.1E-03 −0.18 5.0E-01 Validated in human 5
  1. In a pan-cancer analysis, genes were identified that showed a significant (anti-)correlation (correlation coefficient Rho < − 0.184 or Rho > 0.186 and, p < 0.01) between telomere length and gene expression. For the calculations, the values for the ratios of tumor over normal tissue were used. The table shows those genes that were listed in the TelNet database with their TM information and TelNet scores