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Table 4 Summary of enriched Gene Ontology (GO) biological process (BP) terms among total identified Pfam protein family domains

From: Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes

term_ID description Frequencya log10 p-value Uniquenessb
GO:0008152 metabolic process 62.92% −4.2076 0.974
GO:0007154 cell communication 28.75% −5.9208 0.866
GO:0006139 nucleobase-containing compound metabolic process 28.16% −31.0655 0.776
GO:0007165 signal transduction 26.76% −18.9208 0.794
GO:0006810 transport 19.48% −32.6383 0.765
GO:0006355 regulation of transcription, DNA-templated 14.27% −8.9586 0.608
GO:0006464 cellular protein modification process 14.26% −11.7212 0.62
GO:0007186 G-protein coupled receptor signaling pathway 8.87% −25.4318 0.803
GO:0006508 proteolyis 7.74% −32.6778 0.741
GO:0006811 ion transport 7.05% −12.2076 0.744
GO:0055114 oxidation-reduction process 6.85% −11.699 0.831
GO:0055085 transmembrane transport 6.54% −32.6383 0.714
GO:0016192 vesicle-mediated transport 4.60% −30.7447 0.785
GO:0006886 intracelular protein transport 3.09% −30.7447 0.792
GO:0016567 protein ubiquitination 2.40% −14.3468 0.673
GO:0006820 anion transport 2.07% −61.2147 0.769
GO:0006457 protein folding 1.00% −19.9208 0.736
GO:0007018 microtubule-based movement 1.00% −45.6021 0.843
GO:0035023 regulation of Rho protein signal transduction 0.92% −11.1675 0.832
GO:0016573 histone acetylation 0.60% −51.3372 0.635
GO:0043401 steroid hormone mediated signaling pathway 0.46% −28.6383 0.839
GO:0045454 cell redox homeostasis 0.40% −27.0269 0.865
GO:0000413 protein peptidyl-prolyl isomerization 0.24% −19.9208 0.709
GO:0006400 tRNA modification 0.20% −34.7447 0.692
GO:0018149 peptide cross-linking 0.17% −13.4318 0.731
GO:0007099 centriole replication 0.08% − 153.347 0.832
GO:0009396 folic acid-containing compound biosynthetic process 0.05% −11.699 0.786
  1. aFrequency represents the proportion of the specified GO term within the entire Bos Taurus species-specific Uniprot protein annotation database. Higher frequencies represent more general and common terms, while terms with a lower frequency are rare and specific
  2. bUniqueness represents whether a term is an outlier when compared semantically to the list as a whole