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Table 4 Summary of enriched Gene Ontology (GO) biological process (BP) terms among total identified Pfam protein family domains

From: Genome sequencing and protein domain annotations of Korean Hanwoo cattle identify Hanwoo-specific immunity-related and other novel genes

term_ID

description

Frequencya

log10 p-value

Uniquenessb

GO:0008152

metabolic process

62.92%

−4.2076

0.974

GO:0007154

cell communication

28.75%

−5.9208

0.866

GO:0006139

nucleobase-containing compound metabolic process

28.16%

−31.0655

0.776

GO:0007165

signal transduction

26.76%

−18.9208

0.794

GO:0006810

transport

19.48%

−32.6383

0.765

GO:0006355

regulation of transcription, DNA-templated

14.27%

−8.9586

0.608

GO:0006464

cellular protein modification process

14.26%

−11.7212

0.62

GO:0007186

G-protein coupled receptor signaling pathway

8.87%

−25.4318

0.803

GO:0006508

proteolyis

7.74%

−32.6778

0.741

GO:0006811

ion transport

7.05%

−12.2076

0.744

GO:0055114

oxidation-reduction process

6.85%

−11.699

0.831

GO:0055085

transmembrane transport

6.54%

−32.6383

0.714

GO:0016192

vesicle-mediated transport

4.60%

−30.7447

0.785

GO:0006886

intracelular protein transport

3.09%

−30.7447

0.792

GO:0016567

protein ubiquitination

2.40%

−14.3468

0.673

GO:0006820

anion transport

2.07%

−61.2147

0.769

GO:0006457

protein folding

1.00%

−19.9208

0.736

GO:0007018

microtubule-based movement

1.00%

−45.6021

0.843

GO:0035023

regulation of Rho protein signal transduction

0.92%

−11.1675

0.832

GO:0016573

histone acetylation

0.60%

−51.3372

0.635

GO:0043401

steroid hormone mediated signaling pathway

0.46%

−28.6383

0.839

GO:0045454

cell redox homeostasis

0.40%

−27.0269

0.865

GO:0000413

protein peptidyl-prolyl isomerization

0.24%

−19.9208

0.709

GO:0006400

tRNA modification

0.20%

−34.7447

0.692

GO:0018149

peptide cross-linking

0.17%

−13.4318

0.731

GO:0007099

centriole replication

0.08%

− 153.347

0.832

GO:0009396

folic acid-containing compound biosynthetic process

0.05%

−11.699

0.786

  1. aFrequency represents the proportion of the specified GO term within the entire Bos Taurus species-specific Uniprot protein annotation database. Higher frequencies represent more general and common terms, while terms with a lower frequency are rare and specific
  2. bUniqueness represents whether a term is an outlier when compared semantically to the list as a whole