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Table 3 Methylation effect estimates stratified by genotype at SNPs with significant interaction effects

From: Do changes in DNA methylation mediate or interact with SNP variation? A pharmacoepigenetic analysis

SNP

Ref. allele

Alt. allele

No. alt alleles

No.

CpG site

Beta

SE

p Value

rs4686740

A

G

0

124

cg21463380

−0.11728

0.579811

0.84

1

190

1.576491

0.558714

0.0048

2

89

1.597208

0.594223

0.0072

rs17216446

C

A

0

124

cg15395354

0.409902

0.382098

0.28

1

195

0.366537

0.338832

0.28

2

76

2.026818

0.669214

0.0025

  1. Alt alternate, No number, Ref reference