From: Investigation of parent-of-origin effects induced by fenofibrate treatment on triglycerides levels
SNP | Chr:Pos (Mb) | Gene | Pheno | Alleles a1/a2 | Freq a1 | TGs = SNP + covariates | TGs = Meth2 + covariates | Meth2 = SNP + covariates + TGs | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P | P of† | P ot† | P om_op† | P op_om† | Probe | Pos (Mb) | P | P | P of† | P ot† | P om_op† | P op_om† | ||||||
rs2903839 | 2:56.17 | TG1–2 | A/G | 0.59 | 0.16 | 2.7 × 10−7 | 1.5 × 10− 7 | 1.8 × 10− 6 | 0.01 | cg07468585 | 56.2 | 0.02 | 0.53 | 0.02 | 0.39 | 0.21 | 0.01 | |
cg25249448 | 56.2 | 0.03 | 0.55 | 0.04 | 0.16 | 0.62 | 0.01 | |||||||||||
rs13131918 | 4:24.87 | CCDC149 | TG1–2 | A/G | 0.52 | 0.07 | 2.8 × 10−7 | 1.4 × 10−7 | 0.004 | 7.0 × 10−7 | cg09490880 | 24.9 | 0.04 | 0.02 | 0.72 | 0.52 | 0.42 | 0.85 |
rs7300117 | 12:131.7 | TG1–2 | A/T | 0.52 | 6.2 × 10−9 | 3.8 × 10−5 | 0.07 | 0.11 | 3.9 × 10− 5 | cg09481537 | 131.7 | 0.04 | 0.09 | 0.06 | 0.16 | 0.70 | 0.02 | |
rs301621 | 16:86.65 | ΔTG1–4 | G/T | 0.60 | 0.18 | 1.5 × 10−5 | 0.01 | 0.40 | 1.2 × 10− 5 | cg10206250 | 86.6 | 0.04 | 0.19 | 0.02 | 0.008 | 0.01 | 0.10 | |
rs10417097* | 19:19.72 | PBX4 | TG1–2 | C/G | 0.62 | 0.01 | 3.0 × 10−5 | 6.4 × 10−5 | 0.23 | 8.0 × 10−6 | cg10738025 | 19.7 | 0.03 | 0.005 | 0.47 | 0.92 | 0.34 | 0.49 |
rs10417097* | 19:19:72 | PBX4 | TG3–4 | C/G | 0.62 | 0.009 | 3.0 × 10−6 | 6.8 × 10−6 | 0.13 | 8.5 × 10−7 | – | – | – | – | – | – | – | – |