Skip to main content

Advertisement

Table 3 Genotypes of 6 SNPs

From: Association between MKRN3 and LIN28B polymorphisms and precocious puberty

Genotype Girls Boys
Prepuberty (%) Precocoious puberty (%) Prepuberty (%) Precocious puberty (%)
rs2239669a,b
 CC 58 (62.4) 4 (57.1) 26 (59.1) 9 (36.0)
 CT 28 (30.1) 2 (28.6) 17 (38.6) 11 (44.0)
 TT 7 (7.5) 1 (14.3) 1 (2.3) 5 (20.0)
rs6576457a,c
 GG 59 (62.8) 4 (57.1) 26 (59.1) 9 (34.6)
 GA 26 (27.7) 2 (28.6) 17 (38.6) 11 (42.3)
 AA 9 (9.6) 1 (14.3) 1 (2.3) 6 (23.1)
rs12441827d,e
 TT 44 (45.80) 2 (28.6) 11 (25.0) 17 (65.4)
 TC 38 (39.6) 5 (71.4) 30 (68.2) 8 (30.8)
 CC 14 (14.6) 0 (0) 3 (6.8) 1 (3.8)
rs12148769
 GG 51 (53.1) 3 (42.9) 21 (47.7) 15 (57.7)
 GA 36 (37.5) 3 (42.9) 20 (45.5) 11 (42.3)
 AA 9 (9.4) 1 (14.3) 3 (6.8) 0 (0)
rs314276
 CC 55 (57.3) 3 (42.9) 27 (61.4) 16 (61.5)
 CA 36 (37.5) 3 (42.9) 15 (34.1) 7 (26.9)
 AA 5 (5.2) 1 (14.3) 2 (4.5) 3 (11.5)
rs314280
 AA 5 (5.3) 1 (14.3) 2 (4.5) 3 (11.5)
 GA 35 (36.8) 3 (42.9) 14 (31.8) 7 (26.9)
 GG 55 (57.9) 3 (42.9) 28 (63.6) 16 (61.5)
  1. aP < 0.01 for additive model (minor allele homozygotes versus heterozygotes) in boys
  2. bP < 0.05 for recessive model in boys
  3. cP < 0.01 for recessive model in boys
  4. dP < 0.0001 for additive model (major allele homozygotes versus heterozygotes) in boys
  5. eP < 0.01 for dominant model in boys