Fig. 4From: Skeletal muscle in aged mice reveals extensive transformation of muscle gene expressionDegenerated myofilaments and mitochondrial breakdown in the muscle of aged mice. Ultrastructure of the rectus femoris from male mice (a) at the ages of 3Â months and (b-c) 24Â months old. b Aged rectus femoris muscle displayed large tubular aggregates, formed by SR. c The MVB was enlarged and shown in the aged skeletal muscle. The red arrow indicates the MVB. N, nucleus; m, mitochondria; mf, myofilament; SR, sarcoplasmic reticulum. We performed ultrastructural observation using 4 mice of each age, 5 blocks of each mouse, and 3 grids of each block. We screened each grid and collected more than 5 images for us to show the appropriate and reproducible dataBack to article page