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Table 1 G6PD enzyme activity in the samples with G6PD Orissa, G6PD Mahidol, and G6PD Kalyan-Kerala variants

From: High resolution melting curve analysis enables rapid and reliable detection of G6PD variants in heterozygous females

Mutations Exons Amino acid substitution Enzyme activity U/g Hb Enzyme activity compared to the cut-off (%)
c.C131G* Exon 3 p. Ala44Gly 3.10 57.93% ↓
c.C131G# Exon 3 p. Ala44Gly 4.89 33.60% ↓
c.G487A# Exon 6 p. Gly163Ser 7.67 03.91% ↑
c.G487A# Exon 6 p. Gly163Ser 11.34 35.04% ↑
c.G949A# Exon 9 p. Glu317Lys 5.45 26.03% ↓
c.G949A# Exon 9 p. Glu317Lys 9.38 21.45% ↑
c.G949A# Exon 9 p. Glu317Lys 10.84 33.99% ↑
  1. # indicates heterozygous variants; *indicates homozygous variants; ↓ indicates lower; ↑ indicates higher