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Table 1 Genes with the most significant differences in expression between normal colon and primary tumours

From: Exome scale map of genetic alterations promoting metastasis in colorectal cancer

RefSeq ID gene symbol gene name FC adjusted p-value
NM_001898 CST1 cystatin SN 131.6 3E-25
NM_005978 S100A2 S100 calcium binding protein A2 88.7 1.45E-27
NM_182507 KRT80 keratin 80 52.9 8.81E-21
NM_178493 NOTUM NOTUM, palmitoleoyl-protein carboxylesterase 46.6 3.01E-17
NM_005069 SIM2 single-minded family bHLH transcription factor 2 44.2 1.15E-18
NM_001201 BMP3 bone morphogenetic protein 3 0.0217 3.34E-15
NM_182546 VSTM2A V-set and transmembrane domain containing 2A 0.0170 6.77E-14
NM_001169 AQP8 aquaporin 8 0.0169 3.01E-17
NM_001285 CLCA1 chloride channel accessory 1 0.0164 5.46E-17
NM_152338 ZG16 zymogen granule protein 16 0.0142 2.53E-14
NM_000067 CA2 carbonic anhydrase 2 0.0135 2.33E-42
NM_005182 CA7 carbonic anhydrase 7 0.0129 9.63E-16
NM_001134742 SLC4A4 solute carrier family 4 member 4 0.0120 2.19E-27
NM_001128831 CA1 carbonic anhydrase 1 0.0083 9.96E-18
NM_206832 TMIGD1 transmembrane and immunoglobulin domain containing 1 0.0078 7.55E-21
NM_007102 GUCA2B guanylate cyclase activator 2B 0.0053 1.03E-30
  1. FC - fold change (expression in primary tumours/expression in normal colon)