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Table 2 Genes with the most significant differences in expression between primary tumours and metastases

From: Exome scale map of genetic alterations promoting metastasis in colorectal cancer

RefSeq ID gene symbol gene name FC adjusted p-value
NM_000567 CRP C-reactive protein 85.0 2.36E-21
NM_021870 FGG fibrinogen gamma chain 56.0 1.98E-12
NM_001204307 GC GC, vitamin D binding protein 29.1 1.19E-08
NM_002216 ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 26.1 1.43E-06
NM_005141 FGB fibrinogen beta chain 25.1 4.18E-05
NM_000042 APOH apolipoprotein H 22.2 4.18E-05
NM_002215 ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 22.0 1.81E-05
NM_000607 ORM1 orosomucoid 1 16.0 8E-06
NM_004467 FGL1 fibrinogen like 1 14.2 0.003387
NM_001063 TF transferrin 12.9 0.000902
NM_000505 F12 coagulation factor XII 12.3 0.003333
NM_145285 NKX2–3 NK2 homeobox 3 0.055 2.63E-07
NM_003480 MFAP5 microfibrillar associated protein 5 0.068 6.59E-05
NM_004950 EPYC epiphycan 0.070 0.001189
NM_002148 HOXD10 homeobox D10 0.071 7.38E-05
NM_001170807 FHL5 four and a half LIM domains 5 0.078 4.18E-05
NM_001145311 PLIN1 perilipin 1 0.080 0.001189
NM_019849 SLC7A10 solute carrier family 7 member 10 0.080 0.00042
  1. FC - fold change (expression in metastases/expression in primary tumours)