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Table 3 GO terms significant for normal colon - primary tumour - metastasis transition

From: Exome scale map of genetic alterations promoting metastasis in colorectal cancer

GO ID

GO name

adjusted p-value

count

expected count

A

 GO:0015711

organic anion transport

3.64E-03

51

25.2

 GO:0006811

ion transport

3.64E-03

44

20.8

 GO:0034440

lipid oxidation

6.15E-03

27

10.5

 GO:0061326

renal tubule development

2.46E-02

24

9.7

 GO:0006730

one-carbon metabolic process

2.46E-02

11

2.7

 GO:0042493

response to drug

2.46E-02

54

30.6

 GO:0006635

fatty acid beta-oxidation

4.01E-02

12

3.3

 GO:0030214

hyaluronan catabolic process

4.13E-02

8

1.6

 GO:0072163

mesonephric epithelium development

4.13E-02

24

10.3

B

 GO:0016043

cellular component organization

1.03E-03

42

18.3

 GO:0030198

extracellular matrix organization

3.29E-03

40

18.1

 GO:0002576

platelet degranulation

3.72E-03

28

10.9

 GO:0006953

acute-phase response

3.72E-03

17

4.9

 GO:0034367

macromolecular complex remodeling

1.67E-02

11

2.6

 GO:0010951

negative regulation of endopeptidase activity

1.81E-02

27

11.5

 GO:0044057

regulation of system process

1.81E-02

60

35.1

 GO:0007204

positive regulation of cytosolic calcium ion concentration

1.81E-02

45

24.0

 GO:0006559

L-phenylalanine catabolic process

2.45E-02

7

1.2