Skip to main content

Advertisement

Table 3 GO terms significant for normal colon - primary tumour - metastasis transition

From: Exome scale map of genetic alterations promoting metastasis in colorectal cancer

GO ID GO name adjusted p-value count expected count
A
 GO:0015711 organic anion transport 3.64E-03 51 25.2
 GO:0006811 ion transport 3.64E-03 44 20.8
 GO:0034440 lipid oxidation 6.15E-03 27 10.5
 GO:0061326 renal tubule development 2.46E-02 24 9.7
 GO:0006730 one-carbon metabolic process 2.46E-02 11 2.7
 GO:0042493 response to drug 2.46E-02 54 30.6
 GO:0006635 fatty acid beta-oxidation 4.01E-02 12 3.3
 GO:0030214 hyaluronan catabolic process 4.13E-02 8 1.6
 GO:0072163 mesonephric epithelium development 4.13E-02 24 10.3
B
 GO:0016043 cellular component organization 1.03E-03 42 18.3
 GO:0030198 extracellular matrix organization 3.29E-03 40 18.1
 GO:0002576 platelet degranulation 3.72E-03 28 10.9
 GO:0006953 acute-phase response 3.72E-03 17 4.9
 GO:0034367 macromolecular complex remodeling 1.67E-02 11 2.6
 GO:0010951 negative regulation of endopeptidase activity 1.81E-02 27 11.5
 GO:0044057 regulation of system process 1.81E-02 60 35.1
 GO:0007204 positive regulation of cytosolic calcium ion concentration 1.81E-02 45 24.0
 GO:0006559 L-phenylalanine catabolic process 2.45E-02 7 1.2