Skip to main content
Fig. 5 | BMC Genetics

Fig. 5

From: Combining controls can improve power in two-stage association studies

Fig. 5

Replication with shared controls. Red and blue shaded areas are regions where a pair of observed Z scores are deemed a ‘hit’ in the (+,+) quadrant under method A/B respectively. The value zm is almost linearly dependent on (zd,zr) and on (zd,zs) (Additional file 1: Appendix 1). Solid red/blue ellipses indicate contours of the distribution of observed Z scores for a typical non-null SNP under methods A and B, and dashed ellipses indicate contours for a null SNP

Back to article page