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Fig. 4 | BMC Genetics

Fig. 4

From: A statistical measure for the skewness of X chromosome inactivation based on family trios

Fig. 4

Estimated powers of LRT against γ under MP5 and MP6 with ρ=0 and λ2=2. The results are based on 10,000 replicates and 5% significance level. a (pm, pf) = (0.30, 0.30) and γ0=0; b (pm, pf) = (0.30, 0.30) and γ0=1; c (pm, pf) = (0.30, 0.30) and γ0=2; d (pm, pf) = (0.25, 0.30) and γ0=0; e (pm, pf) = (0.25, 0.30) and γ0=1; f (pm, pf) = (0.25, 0.30) and γ0=2; g (pm, pf) = (0.30, 0.25) and γ0=0; h (pm, pf) = (0.30, 0.25) and γ0=1; i (pm, pf) = (0.30, 0.25) and γ0=2. Note that γ0=0, 1 and 2 represent XCI skewing completely against mutant allele, random XCI and XCI skewing completely toward mutant allele, respectively

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