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Table 1 Gene Enrichment of targets in WT group

From: p.E95K mutation in Indian hedgehog causing brachydactyly type A1 impairs IHH/Gli1 downstream transcriptional regulation

GO biological process complete Mus musculus - REFLIST (22262) Gene sets in WT Expected Over/under Fold Enrichment Raw P-value FDR
Sensory perception of smell (GO:0007608) 1089 82 34.05 + 2.41 1.33E-12 2.05E-08
Sensory perception of chemical stimulus (GO:0007606) 1377 92 43.05 + 2.14 2.91E-11 1.49E-07
G-protein coupled receptor signaling pathway (GO:0007186) 1793 111 56.06 + 1.98 1.73E-11 1.33E-07
Sensory perception (GO:0007600) 1757 102 54.93 + 1.86 4.68E-09 1.20E-05
Nervous system process (GO:0050877) 2120 115 66.28 + 1.74 1.72E-08 3.77E-05
System process (GO:0003008) 2592 133 81.04 + 1.64 2.42E-08 4.14E-05
Signaling (GO:0023052) 4966 227 155.26 + 1.46 7.79E-10 3.00E-06
Cell communication (GO:0007154) 5084 231 158.95 + 1.45 1.04E-09 3.20E-06
Signal transduction (GO:0007165) 4629 206 144.72 + 1.42 6.62E-08 1.02E-04
Multicellular organismal process (GO:0032501) 7058 293 220.66 + 1.33 1.77E-08 3.41E-05
Cellular response to stimulus (GO:0051716) 6089 242 190.37 + 1.27 2.37E-05 2.80E-02
Cellular process (GO:0009987) 13,831 486 432.41 + 1.12 2.96E-05 3.25E-02
Biological_process (GO:0008150) 20,540 671 642.16 + 1.04 1.17E-05 1.50E-02
Unclassified (UNCLASSIFIED) 1722 25 53.84 0.46 1.17E-05 1.64E-02