Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation

BMC Genomic Data

Table 1 Descriptive statistics of the different EWAS time-points with distributions of covariates

Age^a (months) [sd]	N	Sex	N Parity (nulliparous) [%]	N Maternal smoking (never) [%]	Maternal age (years) [sd]	N Maternal education (O-levels or lower) [%]
SHBG
117.8 [2.7]	113	Males	54 [47.8]	100 [88.5]	30.5 [4.2]	45 [39.8]
184.7 [3.4]	359	Females	179 [49.9]	314 [87.5]	29.6 [4.2]	180 [50.1]
211.8 [3.9]	114	Males	55 [48.2]	103 [90.4]	30.9 [4.4]	41 [36.0]
Total testosterone^b
117.8 [2.7]	113	Males	54 [47.8]	100 [88.5]	30.5 [4.2]	45 [39.8]
184.8 [3.4]	375	Females	182 [48.5]	329 [87.7]	29.6 [4.2]	191 [50.9]
211.8 [3.9]	113	Males	55 [48.7]	102 [90.3]	30.9 [4.4]	40 [35.4]
Bioavailable testosterone
117.8 [2.7]	113	Males	54 [47.8]	100 [88.5]	30.5 [4.2]	45 [39.8]
211.8 [3.9]	113	Males	55 [48.7]	102 [90.3]	30.9 [4.4]	40 [35.4]

^aAge at time of hormone measurement
^bTotal testosterone standardized for exact age and time-of-venipuncture in males but not in females

ISSN: 2730-6844