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Fig. 1 | BMC Genetics

Fig. 1

From: The main WAP isoform usually found in camel milk arises from the usage of an improbable intron cryptic splice site in the precursor to mRNA in which a GC-AG intron occurs

Fig. 1

Multiple sequences alignment of WAP among Eutherian species including camel (NCBI, LOC105095719), pig (O46655), dog (GenBank AAEX02035361, positions 25,184-23,606), rabbit (P09412), rat (G3 V718), and mouse (Q7M748). Four exons: E1, E3, E4 and E6 (numbering of the putative ancestral gene, proposed by [7], are given in black boxes. Exons 3 and 4 represent 4-DSC domains (DI and DIIA), while exons 1 and 6 indicate the signal peptide (SP) with the N-terminal part (N-ter) of the mature protein and the C-terminal part (C-ter) of the protein, respectively. WAP motifs are boxed in pink. Conserved Cysteine residues (C) in each 4-DSC domain are pink shaded. Residues identical in more than 3 animal species are grey shaded. Gaps are introduced to maximize similarities. Tetrapeptide VSSP, that is specific to camel WAP, is highlighted in yellow

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