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Table 1 Type I error comparison of three methods for different types of phenotypes

From: An integrative U method for joint analysis of multi-level omic data

phenotype distributions Bernoulli Gaussian T 2 T 4 DE
IU 0.048 0.049 0.052 0.055 0.052
VCT 0.046 0.053 0.091 0.068 0.075
Adj-SKAT 0.035 0.055 0.129 0.062 0.064
  1. Bernoulli, Gaussian, T, and DE correspond to Binary, Gaussian-distributed, T-distributed, and Double-exponential distributed phenotypes. The nominal size of the test is 0.05 and n=200