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Table 6 Characterization of predicted deleterious and high impact SNPs annotated in 11 positional candidate genes

From: Unraveling genomic associations with feed efficiency and body weight traits in chickens through an integrative approach

GeneGGASNP IDPosition1AnnotationSIFT scoreAA substitution
AKR1D11rs31637074356,636,977Deleterious0.01Met/Ile
HSP90AB13rs73795983330,358,254Deleterious0.03Thr/Ala
rs73762340530,357,799High impact (Stop lost)*/Arg
KLB4rs74053834869,722,817Deleterious0.02Arg/Trp
RBM474rs31317716369,358,984Deleterious0.00Arg/Cys
PPARGC1A4rs73999031974,565,856Deleterious0.00Arg/Gly
rs1643558474,566,888Deleterious0.01Asp/Asn
rs73175289974,590,596Deleterious0.01Asn/Asp
NR4A27g.36224286C > T (Novel)36,224,286Deleterious0.00Val/Met
g.36225242G > T (Novel)36,225,242Deleterious0.00Arg/Ser
g.36225278C > T (Novel)36,225,278Deleterious0.01Val/Met
ACVR17rs31254118636,479,417Deleterious0.01Trp/Arg
GRIN2A14rs3162410999,451,676High impact (Splice acceptor)
KCNJ524rs3123004401,075,890Deleterious0.02Leu/Pro
SLC35B127g.3338981C > T (Novel)3,338,981High impact (Stop gained)Gln/*
ANGPTL428g.846035G > A (Novel)846,035Deleterious0.03Ser/Phe
  1. 1Position based on assembly Gallus_gallus-5.0