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Table 1 Mean -log10p for non-eQTL and eQTL breast cancer OncoArray SNPs. The eQTLs are stratified by tissue types. Only gray zone SNPs (0.05 > p > 5 × 10− 8) were used in this analysis

From: SNP eQTL status and eQTL density in the adjacent region of the SNP are associated with its statistical significance in GWA studies

eQTL tissue type

non-eQTL SNP

eQTL SNP

aMW(Z)

P

-log10pb

N

-log10pb

N

Esophagus Mucosa

2.01/1.83

1,044,642

2.27/2.04

1556

11.99

2.56E-32

Thyroid

2.01/1.83

1,044,339

2.24/2.01

1859

11.55

4.40E-30

Nerve Tibial

2.01/1.83

1,044,334

2.22/2

1864

10.64

1.02E-25

Pancreas

2.01/1.83

1,045,104

2.28/2.05

1094

10.42

1.03E-24

Artery Aorta

2.01/1.83

1,044,905

2.25/2.02

1293

10.34

2.45E-24

Skin Not Sun Exposed Suprapubic

2.01/1.83

1,044,670

2.23/2.01

1528

10.16

1.56E-23

Lung

2.01/1.83

1,044,615

2.22/2

1583

10.1

2.80E-23

Stomach

2.01/1.83

1,045,249

2.28/2.05

949

9.75

8.90E-22

Adipose Subcutaneous

2.01/1.83

1,044,510

2.21/1.99

1688

9.75

9.52E-22

Muscle Skeletal

2.01/1.83

1,044,683

2.22/2

1515

9.74

9.64E-22

Esophagus Muscularis

2.01/1.83

1,044,642

2.22/2

1556

9.6

4.00E-21

Testis

2.01/1.83

1,044,391

2.2/1.98

1807

9.39

2.77E-20

Esophagus Gastroesophageal Junction

2.01/1.83

1,045,177

2.26/2.03

1021

9.36

3.63E-20

Colon Sigmoid

2.01/1.83

1,045,157

2.25/2.02

1041

9.35

4.16E-20

Skin Sun Exposed Lower leg

2.01/1.83

1,044,398

2.19/1.97

1800

9.15

2.53E-19

Adipose Visceral Omentum

2.01/1.83

1,044,921

2.23/2.01

1277

9.14

2.89E-19

Heart Left Ventricle

2.01/1.83

1,045,132

2.24/2.01

1066

8.94

1.70E-18

Cells Transformed fibroblasts

2.01/1.83

1,044,639

2.2/1.98

1559

8.88

2.98E-18

Artery Coronary

2.01/1.83

1,045,557

2.3/2.06

641

8.78

7.49E-18

Artery Tibial

2.01/1.83

1,044,545

2.19/1.97

1653

8.58

3.99E-17

Brain Cerebellum

2.01/1.83

1,045,002

2.21/1.99

1196

8.38

2.29E-16

Breast Mammary Tissue

2.01/1.83

1,045,173

2.23/2.01

1025

8.35

2.81E-16

Pituitary

2.01/1.83

1,045,266

2.23/2.01

932

8.13

1.82E-15

Adrenal Gland

2.01/1.83

1,045,270

2.23/2.01

928

7.99

5.29E-15

Heart Atrial Appendage

2.01/1.83

1,045,051

2.2/1.98

1147

7.75

3.56E-14

Colon Transverse

2.01/1.83

1,045,071

2.21/1.99

1127

7.75

3.71E-14

Cells EBV-transformed lymphocytes

2.01/1.83

1,045,617

2.28/2.05

581

7.74

3.81E-14

Whole Blood

2.01/1.83

1,045,014

2.2/1.98

1184

7.71

5.10E-14

Spleen

2.01/1.83

1,045,243

2.21/1.99

955

7.29

1.17E-12

Liver

2.01/1.83

1,045,581

2.25/2.02

617

7

9.12E-12

Brain Hypothalamus

2.01/1.83

1,045,693

2.27/2.04

505

6.9

1.79E-11

Prostate

2.01/1.83

1,045,571

2.23/2.01

627

6.65

1.01E-10

Brain Cerebellar Hemisphere

2.01/1.83

1,045,174

2.19/1.97

1024

6.64

1.08E-10

Brain Putamen basal ganglia

2.01/1.83

1,045,561

2.23/2.01

637

6.6

1.36E-10

Brain Caudate basal ganglia

2.01/1.83

1,045,364

2.19/1.97

834

6.24

1.44E-09

Brain Amygdala

2.01/1.83

1,045,805

2.27/2.04

393

6.21

1.72E-09

Vagina

2.01/1.83

1,045,803

2.25/2.02

395

5.7

3.61E-08

Brain Substantia nigra

2.01/1.83

1,045,894

2.28/2.05

304

5.54

8.85E-08

Ovary

2.01/1.83

1,045,627

2.2/1.98

571

5.42

1.66E-07

Brain Frontal Cortex BA9

2.01/1.83

1,045,459

2.18/1.97

739

5.37

2.13E-07

Minor Salivary Gland

2.01/1.83

1,045,836

2.25/2.02

362

5.36

2.25E-07

Brain Anterior cingulate cortex BA24

2.01/1.83

1,045,520

2.18/1.97

678

5.21

5.21E-07

Brain Nucleus accumbens basal ganglia

2.01/1.83

1,045,408

2.17/1.96

790

5.2

5.41E-07

Brain Spinal cord cervical c-1

2.01/1.83

1,045,737

2.2/1.98

461

4.77

4.66E-06

Small Intestine Terminal Ileum

2.01/1.83

1,045,503

2.16/1.95

695

4.66

7.51E-06

Brain Cortex

2.01/1.83

1,045,253

2.13/1.93

945

4.31

3.74E-05

Uterus

2.01/1.83

1,045,780

2.18/1.97

418

4.09

9.19E-05

Brain Hippocampus

2.01/1.83

1,045,658

2.16/1.95

540

4.04

1.12E-04

  1. aMW(Z) is a Z statistics from Mann-Whitney test for comparing two samples
  2. bmean/median
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BMC Genomic Data

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