Fig. 2From: An IL17RA frameshift variant in a Holstein cattle family with psoriasis-like skin alterations and immunodeficiencyDetails of the inguinal skin lesions of case 2. a Macroscopic image of chronic ulcerations with serocellular crusts. b Microscopic view of severe ulceration of the epithelium (arrowheads) with formation of granulation tissue and necrosuppurative inflammation. Hematoxylin and Eosin, 5x, bar = 1 mm. c Microscopic view showing marked orthokeratotic hyperkeratosis (arrowhead). Hematoxylin and Eosin, 10x, bar = 500 μmBack to article page