Amyloid-β peptides slightly affect lifespan or antimicrobial peptide gene expression in Drosophila melanogaster

BMC Genomic Data

Table 1 Influence of Aβ peptides on median and maximum lifespan

Variant	Sex	M (days)	dM (%)	FET (p)	90% (days)	d90% (%)	WAT (p)	n
control	male	56			66			275
Aβ42	male	56	0.0	0.4706	66	0.0	0.464	282
isoD7-Aβ42	male	56	0.0	0.3906	64	−3.0	0.053	282
pS8-Aβ42	male	56	0.0	0.7325	64	−3.0	0.293	278
control	female	67			74			294
Aβ42	female	64	−4.5*	0.0024	71	−4.1	0.078	301
isoD7-Aβ42	female	64	−4.5	0.1668	74	0.0	0.554	258
pS8-Aβ42	female	64	−4.5*	0.0022	74	0.0	0.995	262

M (days) - median lifespan; 90% (days) - age of 90% mortality (maximum lifespan); dM (%), d90% (%), − differences between median and maximum (age of 90% mortality) lifespan of control and experimental flies, respectively; n - number of flies; *p < 0.01, FET - Fisher’s exact test (median lifespan comparison), WAT - Boschloo’s (Wang-Allison) test (maximum lifespan comparison)

ISSN: 2730-6844