Skip to main content
Fig. 2 | BMC Genetics

Fig. 2

From: Disruptive natural selection by male reproductive potential prevents underexpression of protein-coding genes on the human Y chromosome as a self-domestication syndrome

Fig. 2

Measuring the kinetics of TBP binding to two TATA-containing ODNs identical to the human SHOX gene promoter. a and b Electropherograms in the cases of the wild-typed ancestral and minor alleles of the unannotated SNP rs1452787381 under this study, respectively; the concentration of TBP was 2 nM in all the experiments; the concentrations of an ODN containing a tested SNP allele that we used are indicated; c and d dependences of reaction rates on ODN concentrations in the cases of the ancestral and minor alleles of the SNP rs1452787381, respectively; the KD value of the equilibrium dissociation constant was inferred from the dependences of reaction rates on ODN concentrations according to publicly available software GraphPad Prism 5 (http://graphpad-prism.software.informer.com/5.01)

Back to article page

BMC Genomic Data

ISSN: 2730-6844

Contact us