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Table 2 Top 10 DEMs in EC tissues compared with NE tissues according to the data from GEO database

From: Bioinformatic screening for candidate biomarkers and their prognostic values in endometrial cancer

miRNA

logFC

P-value

adj. P-value

upregulated miRNA

 hsa-miR-205

5.717071419

8.28E-10

3.45E-07

 hsa-miR-135b

3.002833732

6.43E-05

1.87E-03

 hsa-miR-182

2.827333932

2.90E-06

2.00E-04

 hsa-miR-183

2.705891835

2.87E-05

1.06E-03

 hsa-miR-429

2.437603498

9.52E-07

9.11E-05

 hsa-miR-200b

2.244848862

1.74E-06

1.37E-04

 hsa-miR-96

2.195969063

7.78E-05

2.14E-03

 hsa-miR-200a

1.973216466

4.25E-05

1.43E-03

 hsa-miR-202

1.943991213

4.19E-03

4.31E-02

 hsa-miR-210

1.715073494

1.94E-04

3.85E-03

downregulated miRNA

 hsa-miR-424

−4.875026249

1.77E-13

3.59E-10

 hsa-miR-143

−4.140227835

5.97E-07

6.07E-05

 hsa-miR-133b

−4.081321667

4.19E-06

2.54E-04

 hsa-miR-376c

−3.636752313

9.60E-05

2.41E-03

 hsa-miR-195

−3.523216268

1.67E-07

2.57E-05

 hsa-miR-204

−3.51217031

7.22E-04

1.10E-02

 hsa-miR-145

−3.493087645

1.82E-05

7.61E-04

 hsa-miR-411

−3.39771373

3.84E-06

2.40E-04

 hsa-miR-381

−3.035325968

4.20E-05

1.41E-03

 hsa-miR-379

−2.971031318

2.79E-06

1.95E-04

  1. DEMs, differentially expressed miRNAs, EC endometrial cancer, NE normal endometrium, miRNA or miR, microRNA, FC, fold-change; adj. P-value, adjusted P-value; adjusted P-value was obtained by correcting P-value using the ‘Benjamini-Horchberg’ method