Fig. 3From: Molecular basis of a new ovine model for human 3M syndrome-2Multiple species partial OBSL1 protein alignment using T-Coffee and BOXSHADE. Accessions used were XP_027821027.1 (Ovis aries), NP_056126.1 (Homo sapiens), XP_003309516.1 (Pan troglodytes), XP_002799127.1 (Macaca mulatta), XP_005640767.1 (Canis lupus familiaris), NP_001068959.2 (Bos taurus), XP_343600.4 (Rattus norvegicus), XP_003641689.2 (Gallus gallus) and NP_001121829.1 (Danio rerio). SheepMT refers to the mutant Ovis aries sequence and SheepWT refers to the wildtype Ovis aries sequence. The predicted frameshift starting with the replacement of valine with tryptophan in position 573 in affected sheep is highlighted by an asterix (*), with the partial new amino acid sequence highlighted in red in the SheepMT sequence, that is predicted to terminate at positon 691Back to article page