Fig. 6From: Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codonPOLG contains a further upstream ORF-Z. a. Schematic of where ORF-Z is located relative to the architecture of POLG. b. Ribosome profiling data mined from GWIPs-viz. The top panel in blue represents initiating ribosomes while the bottom panel in red represents elongating ribosomes. Arrows indicate positions of the initiation codons of all three ORFs, which exactly match peaks in initiating ribosome coverage. c. Weblogo of ORF-Z initiation contexts extracted from mammalian POLG mRNA sequences that contain ORF-Y and at least 150 nucleotides of 5′ UTR. The start codon is underlinedBack to article page