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Complex traits and quantitative genetics

Section edited by Jim Reecy

This section incorporates all aspects of complex trait and quantitative genetics including but not limited to: mapping and association studies, the genetic basis of disease, genetics aspects of breeding and linkage analysis.

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  1. Content type: Research article

    Quantitative traits are common in nature, but quantitative pathogenicity has received only little attention in phytopathology. In this study, we used 100 Fusarium culmorum isolates collected from natural field en...

    Authors: Valheria Castiblanco, Jose J. Marulanda, Tobias Würschum and Thomas Miedaner

    Citation: BMC Genetics 2017 18:49

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  2. Content type: Research article

    Differential plasma concentrations of circulating lipid species are associated with pathogenesis of type 2 diabetes (T2D). Whether the wide inter-individual variability in the plasma lipidome contributes to th...

    Authors: Hemant Kulkarni, Manju Mamtani, Gerard Wong, Jacquelyn M. Weir, Christopher K. Barlow, Thomas D. Dyer, Laura Almasy, Michael C. Mahaney, Anthony G. Comuzzie, Ravindranath Duggirala, Peter J. Meikle, John Blangero and Joanne E. Curran

    Citation: BMC Genetics 2017 18:48

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  3. Content type: Research article

    Due to the great advantages in selection accuracy and efficiency, genomic selection (GS) has been widely studied in livestock, crop and aquatic animals. Our previous study based on one full-sib family of Litopena...

    Authors: Quanchao Wang, Yang Yu, Jianbo Yuan, Xiaojun Zhang, Hao Huang, Fuhua Li and Jianhai Xiang

    Citation: BMC Genetics 2017 18:45

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  4. Content type: Research article

    Eye pigmentation abnormalities in cattle are often related to albinism, Chediak-Higashi or Tietz like syndrome. However, mutations only affecting pigmentation of coat color and eye have also been described. He...

    Authors: Anne K. Hollmann, Martina Bleyer, Andrea Tipold, Jasmin N. Neßler, Wilhelm E. Wemheuer, Ekkehard Schütz and Bertram Brenig

    Citation: BMC Genetics 2017 18:30

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  5. Content type: Research article

    The significant social and economic loss as a result of bovine tuberculosis (bTB) presents a continuous challenge to cattle industries in the UK and worldwide. However, host genetic variation in cattle suscept...

    Authors: Kethusegile Raphaka, Oswald Matika, Enrique Sánchez-Molano, Raphael Mrode, Mike Peter Coffey, Valentina Riggio, Elizabeth Janet Glass, John Arthur Woolliams, Stephen Christopher Bishop and Georgios Banos

    Citation: BMC Genetics 2017 18:27

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  6. Content type: Research article

    With the development of SNP chips, SNP information provides an efficient approach to further disentangle different patterns of genomic variances and covariances across the genome for traits of interest. Due to...

    Authors: Xiujin Li, Mogens Sandø Lund, Luc Janss, Chonglong Wang, Xiangdong Ding, Qin Zhang and Guosheng Su

    Citation: BMC Genetics 2017 18:26

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  7. Content type: Research article

    Potato frying color is an agronomic trait influenced by the sugar content of tubers. The candidate gene approach was employed to elucidate the molecular basis of this trait in Solanum tuberosum Group Phureja, whi...

    Authors: Diana Duarte-Delgado, Deissy Juyó, Christiane Gebhardt, Felipe Sarmiento and Teresa Mosquera-Vásquez

    Citation: BMC Genetics 2017 18:23

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    The Correction to this article has been published in BMC Genetics 2017 18:91

  8. Content type: Research article

    Milk β-lactoglobulin (β-LG) content is of interest as it is associated with nutritional and manufacturing properties. It is known that milk β-LG content is strongly affected by genetic factors. In cattle, most...

    Authors: Nicolas Bedere and Henk Bovenhuis

    Citation: BMC Genetics 2017 18:17

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  9. Content type: Review

    Recent advances in the development of sequencing technologies provide researchers with unprecedented possibilities for genetic analyses. In this review, we will discuss the history of genetic studies and the p...

    Authors: Britt-Sabina Petersen, Broder Fredrich, Marc P. Hoeppner, David Ellinghaus and Andre Franke

    Citation: BMC Genetics 2017 18:14

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  10. Content type: Research article

    One of the most commonly used quality measurements of pork is pH measured 24 h after slaughter. The most probable mode of inheritance for this trait is oligogenic with several known major genes, such as PRKAG3. I...

    Authors: Lucas L. Verardo, Marja-Liisa Sevón-Aimonen, Timo Serenius, Ville Hietakangas and Pekka Uimari

    Citation: BMC Genetics 2017 18:13

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  11. Content type: Research article

    Idiopathic or genetic adult-onset epilepsy is a common neurological disorder in domestic dogs. Genetic association has been reported only with ADAM23 on CFA 37 in few breeds. To identify novel epilepsy genes, we ...

    Authors: Lotta L. E. Koskinen, Eija H. Seppälä, Jutta Weissl, Tarja S. Jokinen, Ranno Viitmaa, Reetta L. Hänninen, Pascale Quignon, Andrea Fischer, Catherine André and Hannes Lohi

    Citation: BMC Genetics 2017 18:8

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  12. Content type: Research article

    FTO gene variants have been associated with obesity phenotypes in sedentary and obese populations, but rarely with skeletal muscle and elite athlete phenotypes.

    Authors: S. M. Heffernan, G. K. Stebbings, L. P. Kilduff, R. M. Erskine, S. H. Day, C. I. Morse, J. S. McPhee, C. J. Cook, B. Vance, W. J. Ribbans, S. M. Raleigh, C. Roberts, M. A. Bennett, G. Wang, M. Collins, Y. P. Pitsiladis…

    Citation: BMC Genetics 2017 18:4

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  13. Content type: Research article

    Nonalcoholic fatty liver disease (NAFLD) is a multifactorial disease caused by interactions between environmental and genetic factors. The SMXA-5 mouse is a high-fat diet-induced fatty liver model established ...

    Authors: Miyako Suzuki, Misato Kobayashi, Tamio Ohno, Shinsaku Kanamori, Soushi Tateishi, Atsushi Murai and Fumihiko Horio

    Citation: BMC Genetics 2016 17:145

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  14. Content type: Research article

    Among SNP markers that become increasingly valuable in molecular breeding of crop plants are the CAPS and dCAPS markers derived from the genes of interest. To date, the number of such gene-based markers is sma...

    Authors: Fakhriddin N. Kushanov, Alan E. Pepper, John Z. Yu, Zabardast T. Buriev, Shukhrat E. Shermatov, Sukumar Saha, Mauricio Ulloa, Johnie N. Jenkins, Abdusattor Abdukarimov and Ibrokhim Y. Abdurakhmonov

    Citation: BMC Genetics 2016 17:141

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  15. Content type: Research article

    The use of wood as an industrial raw material has led to development of plantation forestry, in which trees are planted, managed, and harvested as crops. The productivity of such plantations often exceeds that...

    Authors: Jin S. Xiong, Steven E. McKeand, Fikret Isik, Jill Wegrzyn, David B. Neale, Zhao-Bang Zeng, Luciano da Costa e Silva and Ross W. Whetten

    Citation: BMC Genetics 2016 17:138

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  16. Content type: Research article

    Recombination rate is an essential parameter for many genetic analyses. Recombination rates are highly variable across species, populations, individuals and different genomic regions. Due to the profound influ...

    Authors: Marinela Dukić, Daniel Berner, Marius Roesti, Christoph R. Haag and Dieter Ebert

    Citation: BMC Genetics 2016 17:137

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  17. Content type: Research article

    The importance of the adrenal gland in regard to lactation and reproduction in cattle has been recognized early. Caused by interest in animal welfare and the impact of stress on economically important traits i...

    Authors: Bodo Brand, Markus O. Scheinhardt, Juliane Friedrich, Daisy Zimmer, Norbert Reinsch, Siriluck Ponsuksili, Manfred Schwerin and Andreas Ziegler

    Citation: BMC Genetics 2016 17:135

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    The Erratum to this article has been published in BMC Genetics 2016 17:148

  18. Content type: Research article

    Nitrogen use efficiency is an important breeding trait that can be modified to improve the sustainability of many crop species used in agriculture. Rapeseed is a major oil crop with low nitrogen use efficiency...

    Authors: Anne-Sophie Bouchet, Anne Laperche, Christine Bissuel-Belaygue, Cécile Baron, Jérôme Morice, Mathieu Rousseau-Gueutin, Jean-Eric Dheu, Pierre George, Xavier Pinochet, Thomas Foubert, Olivier Maes, Damien Dugué, Florent Guinot and Nathalie Nesi

    Citation: BMC Genetics 2016 17:131

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  19. Content type: Research article

    Kernel length is an important target trait in barley (Hordeum vulgare L.) breeding programs. However, the number of known quantitative trait loci (QTLs) controlling kernel length is limited. In the present study,...

    Authors: Hong Zhou, Shihang Liu, Yujiao Liu, Yaxi Liu, Jing You, Mei Deng, Jian Ma, Guangdeng Chen, Yuming Wei, Chunji Liu and Youliang Zheng

    Citation: BMC Genetics 2016 17:130

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Page 2 of 12

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