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Complex traits and quantitative genetics

Section edited by Jim Reecy

This section incorporates all aspects of complex trait and quantitative genetics including but not limited to: mapping and association studies, the genetic basis of disease, genetics aspects of breeding and linkage analysis.

Page 3 of 12
  1. Content type: Research article

    Spotted wilt caused by tomato spotted wilt virus (TSWV) is one of the major peanut (Arachis hypogaea L.) diseases in the southeastern United States. Occurrence, severity, and symptoms of spotted wilt disease are ...

    Authors: Yu-Chien Tseng, Barry L. Tillman, Ze Peng and Jianping Wang

    Citation: BMC Genetics 2016 17:128

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  2. Content type: Research article

    Preeclampsia is a common and heterogeneous vascular syndrome of pregnancy. Its genetic risk profile is yet unknown and may vary between individuals and populations. The rs4606 3′ UTR polymorphism of the Regula...

    Authors: Tiina Karppanen, Tea Kaartokallio, Miira M. Klemetti, Seppo Heinonen, Eero Kajantie, Juha Kere, Katja Kivinen, Anneli Pouta, Anne Cathrine Staff and Hannele Laivuori

    Citation: BMC Genetics 2016 17:121

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  3. Content type: Research article

    Results from genome-wide association studies (GWAS) identified many loci and biological pathways that influence adult body mass index (BMI). We aimed to identify if biological pathways related to adult BMI als...

    Authors: Claire Monnereau, Suzanne Vogelezang, Claudia J. Kruithof, Vincent W. V. Jaddoe and Janine F. Felix

    Citation: BMC Genetics 2016 17:120

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  4. Content type: Research article

    Genome-wide association studies of Single Nucleotide Polymorphisms (SNPs) have identified 55 SNPs associated with lung function. However, little is known about the effect of copy number variants (CNVs) on lung...

    Authors: Nick Shrine, Martin D. Tobin, Claudia Schurmann, María Soler Artigas, Jennie Hui, Terho Lehtimäki, Olli T. Raitakari, Craig E. Pennell, Qi Wei Ang, David P. Strachan, Georg Homuth, Sven Gläser, Stephan B. Felix, David M. Evans, John Henderson, Raquel Granell…

    Citation: BMC Genetics 2016 17:116

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  5. Content type: Research article

    Earlobe color is a naturally and artificially selected trait in chicken. As a head furnishing trait, it has been selected as a breed characteristic. Research has demonstrated that white/red earlobe color was r...

    Authors: Changsheng Nie, Zebin Zhang, Jiangxia Zheng, Hongyan Sun, Zhonghua Ning, Guiyun Xu, Ning Yang and Lujiang Qu

    Citation: BMC Genetics 2016 17:115

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  6. Content type: Research article

    In the Western world bovine milk products are an important protein source in human diet. The major proteins in bovine milk are the four caseins (CN), αS1-, αS2-, β-, and k-CN and the two whey proteins, β-LG and α...

    Authors: Bart Buitenhuis, Nina A. Poulsen, Grum Gebreyesus and Lotte B. Larsen

    Citation: BMC Genetics 2016 17:114

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  7. Content type: Research article

    Considerable natural variation for lifespan exists within human and animal populations. Genetically dissecting this variation can elucidate the pathways and genes involved in aging, and help uncover the geneti...

    Authors: Chad A. Highfill, G. Adam Reeves and Stuart J. Macdonald

    Citation: BMC Genetics 2016 17:113

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  8. Content type: Research article

    Down syndrome incidence in humans increases dramatically with maternal age. This is mainly the result of increased meiotic errors, but factors such as differences in abortion rate may play a role as well. Sinc...

    Authors: Shani Stern, David Biron and Elisha Moses

    Citation: BMC Genetics 2016 17:105

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  9. Content type: Research article

    Most agronomical traits of crop species are complex traits controlled by multiple genes and affected by environmental factors. While considerable efforts have been made to fine-map and clone major quantitative...

    Authors: Hong-Wei Zhang, Ye-Yang Fan, Yu-Jun Zhu, Jun-Yu Chen, Si-Bin Yu and Jie-Yun Zhuang

    Citation: BMC Genetics 2016 17:98

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  10. Content type: Methodology article

    Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently requires the identification of the respective phenotypic ...

    Authors: M. Labots, M. C. Laarakker, F. Ohl and H. A. van Lith

    Citation: BMC Genetics 2016 17:95

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  11. Content type: Research article

    The genetic determinism of the calving and suckling performance of beef cows is little known whereas these maternal traits are of major economic importance in beef cattle production systems. This paper aims to...

    Authors: Alexis Michenet, Marine Barbat, Romain Saintilan, Eric Venot and Florence Phocas

    Citation: BMC Genetics 2016 17:88

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  12. Content type: Research article

    The identification of lines resistant to ear diseases is of great importance in maize breeding because such diseases directly interfere with kernel quality and yield. Among these diseases, ear rot disease is w...

    Authors: Jhonathan Pedroso Rigal dos Santos, Luiz Paulo Miranda Pires, Renato Coelho de Castro Vasconcellos, Gabriela Santos Pereira, Renzo Garcia Von Pinho and Marcio Balestre

    Citation: BMC Genetics 2016 17:86

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  13. Content type: Research article

    Genome-wide association studies (GWAS) are a powerful tool for detecting genomic regions explaining variation in phenotype. The objectives of the present study were to identify or refine the positions of genom...

    Authors: Shadi Nayeri, Mehdi Sargolzaei, Mohammed K. Abo-Ismail, Natalie May, Stephen P. Miller, Flavio Schenkel, Stephen S. Moore and Paul Stothard

    Citation: BMC Genetics 2016 17:75

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  14. Content type: Research article

    Fibrotic idiopathic interstitial pneumonias (fIIP) are a group of fatal lung diseases with largely unknown etiology and without definitive treatment other than lung transplant to prolong life. There is strong ...

    Authors: Tasha E. Fingerlin, Weiming Zhang, Ivana V. Yang, Hannah C. Ainsworth, Pamela H. Russell, Rachel Z. Blumhagen, Marvin I. Schwarz, Kevin K. Brown, Mark P. Steele, James E. Loyd, Gregory P. Cosgrove, David A. Lynch, Steve Groshong, Harold R. Collard, Paul J. Wolters, Williamson Z. Bradford…

    Citation: BMC Genetics 2016 17:74

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  15. Content type: Research article

    The SMXA-5 mouse is an animal model of high-fat diet-induced fatty liver. The major QTL for fatty liver, Fl1sa on chromosome 12, was identified in a SM/J × SMXA-5 intercross. The SMXA-5 genome consists of the SM/...

    Authors: Misato Kobayashi, Miyako Suzuki, Tamio Ohno, Kana Tsuzuki, Chie Taguchi, Soushi Tateishi, Teruo Kawada, Young-il Kim, Atsushi Murai and Fumihiko Horio

    Citation: BMC Genetics 2016 17:73

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  16. Content type: Research article

    Tensin2 deficiency results in alterations in podocytes and subsequent glomerular and tubulointerstitial injuries. However, this pathology is critically dependent on genetic background. While the Tensin2-defici...

    Authors: Hayato Sasaki, Junpei Kimura, Ken-Ichi Nagasaki, Kiyoma Marusugi, Takashi Agui and Nobuya Sasaki

    Citation: BMC Genetics 2016 17:69

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  17. Content type: Research article

    Comparing QTL analyses of multiple pair-mating families can provide a better understanding of important allelic variations and distributions. However, most QTL mapping studies in common carp have been based on...

    Authors: Weihua Lv, Xianhu Zheng, Youyi Kuang, Dingchen Cao, Yunqin Yan and Xiaowen Sun

    Citation: BMC Genetics 2016 17:65

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  18. Content type: Research article

    White striping (WS) is an emerging quality defect with adverse consequences for the sensorial, technological, and nutritional qualities of breast meat in broiler chickens. The genetic determinism of this defec...

    Authors: Nabeel Alnahhas, Cécile Berri, Marie Chabault, Pascal Chartrin, Maryse Boulay, Marie Christine Bourin and Elisabeth Le Bihan-Duval

    Citation: BMC Genetics 2016 17:61

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  19. Content type: Research article

    The aim of the present study was to compare the power of single nucleotide polymorphism (SNP)-based genome-wide association study (GWAS) and haplotype-based GWAS for quantitative trait loci (QTL) detection, an...

    Authors: Shuji Sato, Yoshinobu Uemoto, Takashi Kikuchi, Sachiko Egawa, Kimiko Kohira, Tomomi Saito, Hironori Sakuma, Satoshi Miyashita, Shinji Arata, Takatoshi Kojima and Keiichi Suzuki

    Citation: BMC Genetics 2016 17:60

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Page 3 of 12

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