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Complex traits and quantitative genetics

Section edited by Jim Reecy

This section incorporates all aspects of complex trait and quantitative genetics including but not limited to: mapping and association studies, the genetic basis of disease, genetics aspects of breeding and linkage analysis.

Page 4 of 13
  1. Content type: Research article

    Tensin2 deficiency results in alterations in podocytes and subsequent glomerular and tubulointerstitial injuries. However, this pathology is critically dependent on genetic background. While the Tensin2-defici...

    Authors: Hayato Sasaki, Junpei Kimura, Ken-Ichi Nagasaki, Kiyoma Marusugi, Takashi Agui and Nobuya Sasaki

    Citation: BMC Genetics 2016 17:69

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  2. Content type: Research article

    Comparing QTL analyses of multiple pair-mating families can provide a better understanding of important allelic variations and distributions. However, most QTL mapping studies in common carp have been based on...

    Authors: Weihua Lv, Xianhu Zheng, Youyi Kuang, Dingchen Cao, Yunqin Yan and Xiaowen Sun

    Citation: BMC Genetics 2016 17:65

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  3. Content type: Research article

    White striping (WS) is an emerging quality defect with adverse consequences for the sensorial, technological, and nutritional qualities of breast meat in broiler chickens. The genetic determinism of this defec...

    Authors: Nabeel Alnahhas, Cécile Berri, Marie Chabault, Pascal Chartrin, Maryse Boulay, Marie Christine Bourin and Elisabeth Le Bihan-Duval

    Citation: BMC Genetics 2016 17:61

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  4. Content type: Research article

    The aim of the present study was to compare the power of single nucleotide polymorphism (SNP)-based genome-wide association study (GWAS) and haplotype-based GWAS for quantitative trait loci (QTL) detection, an...

    Authors: Shuji Sato, Yoshinobu Uemoto, Takashi Kikuchi, Sachiko Egawa, Kimiko Kohira, Tomomi Saito, Hironori Sakuma, Satoshi Miyashita, Shinji Arata, Takatoshi Kojima and Keiichi Suzuki

    Citation: BMC Genetics 2016 17:60

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  5. Content type: Research article

    Hybrid breakdown has been well documented in various species. Relationships between genomic heterozygosity and traits-fitness have been extensively explored especially in the natural populations. But correlati...

    Authors: Baosheng Dai, Huanle Guo, Cong Huang, Xianlong Zhang and Zhongxu Lin

    Citation: BMC Genetics 2016 17:58

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  6. Content type: Research article

    Residual biomass production for fuel conversion represents a unique opportunity to avoid concerns about compromising food supply by using dedicated feedstock crops. Developing tomato varieties suitable for bot...

    Authors: G. Caruso, L. D. Gomez, F. Ferriello, A. Andolfi, C. Borgonuovo, A. Evidente, R. Simister, S. J. McQueen-Mason, D. Carputo, L. Frusciante and M. R. Ercolano

    Citation: BMC Genetics 2016 17:56

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  7. Content type: Research article

    The Nordic Red Cattle consisting of three different populations from Finland, Sweden and Denmark are under a joint breeding value estimation system. The long history of recording of production and health trait...

    Authors: T. Iso-Touru, G. Sahana, B. Guldbrandtsen, M. S. Lund and J. Vilkki

    Citation: BMC Genetics 2016 17:55

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  8. Content type: Research article

    Artificial insemination is widely used in many cattle breeding programs. Semen samples of breeding bulls are collected and closely examined immediately after collection at artificial insemination centers. Only...

    Authors: Hubert Pausch, Heli Venhoranta, Christine Wurmser, Kalle Hakala, Terhi Iso-Touru, Anu Sironen, Rikke K. Vingborg, Hannes Lohi, Lennart Söderquist, Ruedi Fries and Magnus Andersson

    Citation: BMC Genetics 2016 17:49

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  9. Content type: Research article

    Reproductive efficiency has a great impact on the economic success of pork production. Gilts comprise a significant portion of breeding females and gilts that reach puberty earlier tend to stay in the herd lon...

    Authors: Dan J. Nonneman, James F. Schneider, Clay A. Lents, Ralph T. Wiedmann, Jeffrey L. Vallet and Gary A. Rohrer

    Citation: BMC Genetics 2016 17:50

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  10. Content type: Research article

    Although the effect of the fat mass and obesity-associated (FTO) gene on adiposity is well established, there is a lack of evidence whether physical activity (PA) modifies the effect of FTO variants on obesity...

    Authors: Joon Young Kim, Jacob T. DeMenna, Sobha Puppala, Geetha Chittoor, Jennifer Schneider, Ravindranath Duggirala, Lawrence J. Mandarino, Gabriel Q. Shaibi and Dawn K. Coletta

    Citation: BMC Genetics 2016 17:47

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  11. Content type: Research article

    Colorectal cancer is an abnormal tissue development in the colon or rectum. Most of CRCs develop due to somatic mutations, while only a small proportion is caused by inherited mutations. Familial adenomatous p...

    Authors: Alexandra Dorman, Daria Baer, Ian Tomlinson, Richard Mott and Fuad A. Iraqi

    Citation: BMC Genetics 2016 17:46

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    The Erratum to this article has been published in BMC Genetics 2016 17:147

  12. Content type: Research article

    Genetic susceptibility plays an important role in the risk of developing pain in individuals with cancer. As a complex trait, multiple genes underlie this susceptibility. We used gene network analyses to ident...

    Authors: Cielito C. Reyes-Gibby, Jian Wang, Mary Rose T. Silvas, Robert Yu, Sai-Ching J. Yeung and Sanjay Shete

    Citation: BMC Genetics 2016 17:40

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  13. Content type: Research article

    Heritable factors are well known to increase the risk of cancer in families. Known susceptibility genes account for a small proportion of all colorectal cancer cases. The aim of this study was to identify the ...

    Authors: Jessada Thutkawkorapin, Simone Picelli, Vinaykumar Kontham, Tao Liu, Daniel Nilsson and Annika Lindblom

    Citation: BMC Genetics 2016 17:41

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  14. Content type: Research article

    The existence of moderate to high levels of linkage disequilibrium (LD) between genetic markers and quantitative trait loci (QTL) affecting traits of interest is fundamental for the success of genome-wide asso...

    Authors: Patrícia Biegelmeyer, Claudia C. Gulias-Gomes, Alexandre R. Caetano, Juan P. Steibel and Fernando F. Cardoso

    Citation: BMC Genetics 2016 17:32

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  15. Content type: Research article

    Genetic factors play an important role in hearing loss, contributing to approximately 60 % of cases of congenital hearing loss. Autosomal dominant deafness accounts for approximately 20 % of cases of hereditar...

    Authors: Yongyi Yuan, Xue Gao, Bangqing Huang, Jingqiao Lu, Guojian Wang, Xi Lin, Yan Qu and Pu Dai

    Citation: BMC Genetics 2016 17:33

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  16. Content type: Research article

    Seed dormancy is an adaptive trait employed by flowering plants to avoid harsh environmental conditions for the continuity of their next generations. In cereal crops, moderate seed dormancy could help prevent ...

    Authors: Risper Auma Magwa, Hu Zhao and Yongzhong Xing

    Citation: BMC Genetics 2016 17:28

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  17. Content type: Research article

    Groupers (Epinephelus spp.) have been widely cultivated in China and South-East Asian countries. As a novel hybrid offspring crossed between E. fuscogutatus♀ and E. lanceolatus♂, Hulong grouper exhibits significa...

    Authors: Ying Sun, Chuan-Yu Guo, Deng-Dong Wang, Xiao Feng Li, Ling Xiao, Xinhui Zhang, Xinxin You, Qiong Shi, Guo-Jun Hu, Chao Fang, Hao-Ran Lin and Yong Zhang

    Citation: BMC Genetics 2016 17:24

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  18. Content type: Research article

    The prevalence of Type 2 Diabetes (T2D) mellitus in the past decades, has reached epidemic proportions. Several lines of evidence support the role of genetic variation in the pathogenesis of T2D and insulin re...

    Authors: Hanifa J. Abu-Toamih Atamni, Richard Mott, Morris Soller and Fuad A. Iraqi

    Citation: BMC Genetics 2016 17:10

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  19. Content type: Research article

    In animal breeding, genetic variance for complex traits is often estimated using linear mixed models that incorporate information from single nucleotide polymorphism (SNP) markers using a realized genomic rela...

    Authors: Pernille Sarup, Just Jensen, Tage Ostersen, Mark Henryon and Peter Sørensen

    Citation: BMC Genetics 2016 17:11

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Page 4 of 13

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