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Epigenetics and chromosome biology

Section edited by Cesar Martins

This section incorporates all aspects of chromosome biology and epigenetics including but not limited to: molecular cytogenetics, comparative cytogenetics, studies investigating epigenetics, imprinting, and methylation, cytogenetics and karotyping.

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  1. Content type: Research article

    Both classes of transposable elements (DNA and RNA) are tightly regulated at the transcriptional level leading to the inactivation of transposition via epigenetic mechanisms. Due to the high copies number of t...

    Authors: Sylvaine Renault, Murielle Genty, Alison Gabori, Catherine Boisneau, Charles Esnault, Thomas Dugé de Bernonville and Corinne Augé-Gouillou

    Citation: BMC Genetics 2019 20:17

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  2. Content type: Research article

    Sexual precocity is a common biological phenomenon in animal species. A large number of precocity individuals were identified in Chinese mitten crab Eriocheir sinensis, which caused huge economic loss annually. H...

    Authors: Xiaowen Chen, Jun Wang, Xin Hou, Wucheng Yue, Shu Huang and Chenghui Wang

    Citation: BMC Genetics 2019 20:12

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  3. Content type: Research article

    The re-sequencing of C. angulata has revealed many polymorphisms in candidate genes related to adaptation to abiotic stress that are not present in C. gigas; these genes, therefore, are probably related to the ab...

    Authors: Ismael Cross, Silvia Portela-Bens, Aglaya García-Angulo, Manuel A. Merlo, María E. Rodríguez, Thomas Liehr and Laureana Rebordinos

    Citation: BMC Genetics 2018 19:104

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  4. Content type: Research article

    Fish may display variations in ploidy, including three sets of chromosomes, known as triploidy. A recent study revealed a frequency of ~ 2% spontaneous (i.e., non-intentional) triploidy in domesticated Atlanti...

    Authors: Katarina M Jørgensen, Vidar Wennevik, Anne Grete Eide Sørvik, Laila Unneland, Sergey Prusov, Fernando Ayllon and Kevin A Glover

    Citation: BMC Genetics 2018 19:90

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  5. Content type: Research article

    The Leguminosae family is the third-largest family of angiosperms, and Caesalpinioideae is its second-largest subfamily. A great number of species (approximately 205) are found in the Caesalpinia group within thi...

    Authors: Polliana Silva Rodrigues, Margarete Magalhães Souza, Cláusio Antônio Ferreira Melo, Telma Nair Santana Pereira and Ronan Xavier Corrêa

    Citation: BMC Genetics 2018 19:25

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  6. Content type: Research article

    Puberty is a pivotal stage in female animal development, and marks the onset of reproductive capability. However, little is known about the function of lncRNAs (long noncoding RNAs) in puberty. Therefore, RNA-...

    Authors: Xiaoxiao Gao, Jing Ye, Chen Yang, Lei Luo, Ya Liu, Jianping Ding, Yunhai Zhang, Yinghui Ling, Weiping Huang, Xiaorong Zhang, Kaifa Zhang, Xiumei Li, Jie Zhou, Fugui Fang and Zubing Cao

    Citation: BMC Genetics 2018 19:19

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  7. Content type: Research article

    Study of epigenetics is currently a high-impact research topic. Multi stage methylation is also an area of high-dimensional prospect. In this article, we provide a new study (intra and inter-species study) on ...

    Authors: Ujjwal Maulik, Sagnik Sen, Saurav Mallik and Sanghamitra Bandyopadhyay

    Citation: BMC Genetics 2018 19:9

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  8. Content type: Research article

    Crucian carp is a popular ornamental strain in Asia with variants in body color. To further explore the genetic mechanisms underlying gray and red body color formation in crucian carp, the skin transcriptomes ...

    Authors: Yongqin Zhang, Jinhui Liu, Wen Fu, Wenting Xu, Huiqin Zhang, Shujuan Chen, Wenbin Liu, Liangyue Peng and Yamei Xiao

    Citation: BMC Genetics 2017 18:95

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  9. Content type: Research article

    Satellite DNAs (satDNAs) are organized in repetitions directly contiguous to one another, forming long arrays and composing a large portion of eukaryote genomes. These sequences evolve according to the concert...

    Authors: Diogo Milani, Érica Ramos, Vilma Loreto, Dardo Andrea Martí, Adauto Lima Cardoso, Karen Cristiane Martinez de Moraes, Cesar Martins and Diogo Cavalcanti Cabral-de-Mello

    Citation: BMC Genetics 2017 18:81

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  10. Content type: Research article

    Undernutrition is an increasingly common problem. Insufficient calorie intake and nutrient deficiencies during pregnancy may have an impact not only on the mother, but may also alter metabolism in the infant. ...

    Authors: Joanna Nowacka-Woszuk, Zofia E. Madeja and Agata Chmurzynska

    Citation: BMC Genetics 2017 18:78

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  11. Content type: Research article

    Although Tellinidae is one of the largest and most diverse families of bivalves, its taxonomy is utterly chaotic. This is mainly due to the morphological diversity and homoplasy displayed by their shells and t...

    Authors: Daniel García-Souto, Gonzalo Ríos and Juan J. Pasantes

    Citation: BMC Genetics 2017 18:66

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  12. Content type: Research article

    The levels of circulating cytokines fluctuate with age, acute illness, and chronic disease, and are predictive of mortality; this is also true for patterns of DNA (CpG) methylation. Given that immune cells are...

    Authors: Chris P. Verschoor, Lisa M. McEwen, Vikas Kohli, Christina Wolfson, Dawn ME. Bowdish, Parminder Raina, Michael S. Kobor and Cynthia Balion

    Citation: BMC Genetics 2017 18:57

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  13. Content type: Research article

    MicroRNAs (miRNAs) have a great influence on various physiological functions. A lot of high-throughput sequencing (HTS) research on miRNAs has been executed in the caprine mammary gland at different lactation ...

    Authors: Jinxing Hou, Xiaopeng An, Yuxuan Song, Binyun Cao, Heping Yang, Zhou Zhang, Wenzheng Shen and Yunpu Li

    Citation: BMC Genetics 2017 18:38

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  14. Content type: Research article

    Holocentric chromosomes occur in approximately 750 species of eukaryotes. Among them, the genus Tityus (Scorpiones, Buthidae) has a labile karyotype that shows complex multivalent associations during male meiosis...

    Authors: Bruno Rafael Ribeiro de Almeida, Susana Suely Rodrigues Milhomem-Paixão, Renata Coelho Rodrigues Noronha, Cleusa Yoshiko Nagamachi, Marlyson Jeremias Rodrigues da Costa, Pedro Pereira de Oliveira Pardal, Johne Souza Coelho and Julio Cesar Pieczarka

    Citation: BMC Genetics 2017 18:35

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  15. Content type: Research article

    The Atlantic salmon aquaculture industry is investigating the feasibility of using sterile triploids to mitigate genetic interactions with wild conspecifics, however, studies investigating diploid and triploid...

    Authors: A. C. Harvey, P. G. Fjelldal, M. F. Solberg, T. Hansen and K. A. Glover

    Citation: BMC Genetics 2017 18:34

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  16. Content type: Research article

    Head spot is one of the phenotypes identified in the KFRS4/Kyo rat strain. Although previous linkage analysis suggested that Ednrb, which is frequently involved in coat color variations in various animals, could ...

    Authors: Minako Yoshihara, Tetsuya Sato, Daisuke Saito, Osamu Ohara, Takashi Kuramoto and Mikita Suyama

    Citation: BMC Genetics 2017 18:29

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  17. Content type: Research article

    Acipenseriformes is a basal lineage of ray-finned fishes and comprise 27 extant species of sturgeons and paddlefishes. They are characterized by several specific genomic features as broad ploidy variation, hig...

    Authors: Radka Symonová, Miloš Havelka, Chris T. Amemiya, William Mike Howell, Tereza Kořínková, Martin Flajšhans, David Gela and Petr Ráb

    Citation: BMC Genetics 2017 18:19

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  18. Content type: Research article

    Interspecies hybridization is widely used to achieve heterosis or hybrid vigor, which has been observed and harnessed by breeders for centuries. Natural allopolyploid hybrids generally exhibit more superior he...

    Authors: Wen Huang, Qinbo Qin, Huirong Yang, Shuisheng Li, Chaoqun Hu, Yude Wang, Yong Zhang, Shaojun Liu and Haoran Lin

    Citation: BMC Genetics 2016 17:136

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  19. Content type: Research article

    B chromosomes (Bs) are additional chromosomal elements found in a wide range of eukaryotes including fungi, plants and animals. B chromosomes are still enigmatic despite being the subject of hundreds, even tho...

    Authors: Bruno E. A. Fantinatti and Cesar Martins

    Citation: BMC Genetics 2016 17:119

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  20. Content type: Research article

    The ability to eliminate a parental genome from a eukaryotic germ cell is a phenomenon observed mostly in hybrid organisms displaying an alternative propagation to sexual reproduction. For most taxa, the under...

    Authors: Marie Doležálková, Alexandr Sember, František Marec, Petr Ráb, Jörg Plötner and Lukáš Choleva

    Citation: BMC Genetics 2016 17:100

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  21. Content type: Research article

    Multiple sclerosis (MS) is a complex disorder of the central nervous system whose cause is currently unknown. Evidence is increasing that DNA methylation alterations could be involved in inflammatory and neuro...

    Authors: K. Y. Neven, M. Piola, L. Angelici, F. Cortini, C. Fenoglio, D. Galimberti, A. C. Pesatori, E. Scarpini and V. Bollati

    Citation: BMC Genetics 2016 17:84

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  22. Content type: Research article

    Increasing evidence suggests the involvement of epigenetic processes in the development of schizophrenia and bipolar disorder, and recent reviews have focused on findings in post-mortem brain tissue. A systema...

    Authors: Nina Teroganova, Leah Girshkin, Catherine M. Suter and Melissa J. Green

    Citation: BMC Genetics 2016 17:27

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  23. Content type: Research article

    In mammals, multigenerational environmental effects have been documented by either epidemiological studies in human or animal experiments in rodents. Whether such phenomena also occur in birds for more than on...

    Authors: Jean-Michel Brun, Marie-Dominique Bernadet, Alexis Cornuez, Sophie Leroux, Loys Bodin, Benjamin Basso, Stéphane Davail, Mathilde Jaglin, Michel Lessire, Xavier Martin, Nadine Sellier, Mireille Morisson and Frédérique Pitel

    Citation: BMC Genetics 2015 16:145

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  24. Content type: Research article

    The bisexual fertile tetraploid fish is important in biological evolution. Tetraploid fish fertility is the key factor for stable inheritance. Therefore, elucidating tetraploid fish fertility at the molecular ...

    Authors: Rong Zhou, Yanhong Wu, Min Tao, Chun Zhang and Shaojun Liu

    Citation: BMC Genetics 2015 16:119

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  25. Content type: Research article

    Several reports indicate a commonly deleted chromosomal region independent from, and distal to the TP53 locus in a variety of human tumors. In a previous study, we reported a similar finding in a rat tumor model ...

    Authors: Carola Hedberg Oldfors, Diego Garcia Dios, Anna Linder, Kittichate Visuttijai, Emma Samuelson, Sandra Karlsson, Staffan Nilsson and Afrouz Behboudi

    Citation: BMC Genetics 2015 16:80

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  26. Content type: Research article

    Preeclampsia reduces placental expression and activity of 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2), leading to an increase in fetal glucocordicoids. The latter has been proposed to be associated with ...

    Authors: Wensheng Hu, Xiaoling Weng, Minyue Dong, Yun Liu, Wenjuan Li and Hefeng Huang

    Citation: BMC Genetics 2014 15:96

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  27. Content type: Research article

    X-chromosome inactivation silences one X chromosome in females to achieve dosage compensation with the single X chromosome in males. While most genes are silenced on the inactive X chromosome, the gene for the...

    Authors: Andrew G Chapman, Allison M Cotton, Angela D Kelsey and Carolyn J Brown

    Citation: BMC Genetics 2014 15:89

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  28. Content type: Research article

    Allopolyploids generally undergo bivalent pairing at meiosis because only homologous chromosomes pair up. On the other hand, several studies have documented abnormal chromosome behavior during mitosis and meio...

    Authors: Qinbo Qin, Yude Wang, Juan Wang, Jing Dai, Yun Liu and Shaojun Liu

    Citation: BMC Genetics 2014 15:95

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  29. Content type: Research article

    Mussels of the genus Mytilus present morphologically similar karyotypes that are presumably conserved. The absence of chromosome painting probes in bivalves makes difficult verifying this hypothesis. In this cont...

    Authors: Concepción Pérez-García, Paloma Morán and Juan J Pasantes

    Citation: BMC Genetics 2014 15:84

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  30. Content type: Research article

    Aberrant hypermethylation of gene promoter regions is a primary mechanism by which tumor suppressor genes become inactivated in breast cancer. Epigenetic inactivation of the protein tyrosine phosphatase recept...

    Authors: Shao-ying Li, Rong Li, Yu-li Chen, Li-kuang Xiong, Hui-lin Wang, Lei Rong and Rong-cheng Luo

    Citation: BMC Genetics 2014 15:67

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  31. Content type: Research article

    Hypsiboas species have been divided into seven groups using morphological and genetic characters, but for most of the species, there is no cytogenetic information available. A cytogenetic analysis using conventio...

    Authors: Thais Lemos de Mattos, Ana Carolina Coelho, Carlos Henrique Schneider, David Otávio Carmo Telles, Marcelo Menin and Maria Claudia Gross

    Citation: BMC Genetics 2014 15:43

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  32. Content type: Research article

    Evolution of sturgeons and paddlefishes (order Acipenseriformes) is inherently connected with polyploidization events which resulted in differentiation of ploidy levels and chromosome numbers of present acipen...

    Authors: Miloš Havelka, Martin Hulák, Petr Ráb, Marie Rábová, Dietmar Lieckfeldt, Arne Ludwig, Marek Rodina, David Gela, Martin Pšenička, Dmytro Bytyutskyy and Martin Flajšhans

    Citation: BMC Genetics 2014 15:5

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  33. Content type: Research article

    The genus Micronycteris is a diverse group of phyllostomid bats currently comprising 11 species, with diploid number (2n) ranging from 26 to 40 chromosomes. The karyotypic relationships within Micronycteris and b...

    Authors: Talita FA Ribas, Luis RR Rodrigues, Cleusa Y Nagamachi, Anderson JB Gomes, Thayse CM Benathar, Patricia CM O’Brien, Fengtang Yang, Malcolm A Ferguson-Smith and Julio C Pieczarka

    Citation: BMC Genetics 2013 14:119

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  34. Content type: Research article

    Hybridization is a useful strategy to alter the genotypes and phenotypes of the offspring. It could transfer the genome of one species to another through combing the different genome of parents in the hybrid o...

    Authors: Weiguo He, Lihua Xie, Tangluo Li, Shaojun Liu, Jun Xiao, Jie Hu, Jing Wang, Qinbo Qin and Yun Liu

    Citation: BMC Genetics 2013 14:110

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  35. Content type: Research article

    Natural polyploidy has played an important role during the speciation and evolution of vertebrates, including anurans, with more than 55 described cases. The species of the Phyllomedusa burmeisteri group are most...

    Authors: Simone Lilian Gruber, Ana Paula Zampieri Silva, Célio Fernando Baptista Haddad and Sanae Kasahara

    Citation: BMC Genetics 2013 14:75

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  36. Content type: Research article

    The taxonomic and phylogenetic relationships of the genus Phyllomedusa have been amply discussed. The marked morphological similarities among some species hamper the reliable identification of specimens and may o...

    Authors: Daniel Pacheco Bruschi, Carmen Sílvia Busin, Luís Felipe Toledo, Gilda Andrade Vasconcellos, Christine Strussmann, Luiz Norberto Weber, Albertina Pimentel Lima, Jucivaldo Dias Lima and Shirlei Maria Recco-Pimentel

    Citation: BMC Genetics 2013 14:70

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  37. Content type: Research article

    The Leporinus genus, belonging to the Anostomidae family, is an interesting model for studies of sex chromosome evolution in fish, particularly because of the presence of heteromorphic sex chromosomes only in som...

    Authors: Patrícia Pasquali Parise-Maltempi, Edson Lourenço da Silva, Willem Rens, Frances Dearden, Patricia CM O’Brien, Vladimir Trifonov and Malcolm A Ferguson-Smith

    Citation: BMC Genetics 2013 14:60

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  38. Content type: Methodology article

    As a well-known epigenomic modification, DNA methylation is found to be common in plants and plays an important role in many biological processes. Relying on the unique feature of methylation-dependent digesti...

    Authors: Xiaojun Huang, Hanlin Lu, Jun-Wen Wang, Liqin Xu, Siyang Liu, Jihua Sun and Fei Gao

    Citation: BMC Genetics 2013 14:56

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  39. Content type: Research article

    hiPSCs are generated through epigenetic reprogramming of somatic tissue. Genomic imprinting is an epigenetic phenomenon through which monoallelic gene expression is regulated in a parent-of-origin-specific man...

    Authors: Hitoshi Hiura, Masashi Toyoda, Hiroaki Okae, Masahiro Sakurai, Naoko Miyauchi, Akiko Sato, Nobutaka Kiyokawa, Hajime Okita, Yoshitaka Miyagawa, Hidenori Akutsu, Koichiro Nishino, Akihiro Umezawa and Takahiro Arima

    Citation: BMC Genetics 2013 14:32

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  40. Content type: Research article

    Hybridogenesis (hemiclonal inheritance) is a kind of clonal reproduction in which hybrids between parental species are reproduced by crossing with one of the parental species. European water frogs (Pelophylax esc...

    Authors: Dmitry Dedukh, Glib Mazepa, Dmitry Shabanov, Juriy Rosanov, Spartak Litvinchuk, Leo Borkin, Alsu Saifitdinova and Alla Krasikova

    Citation: BMC Genetics 2013 14:26

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  41. Content type: Research article

    Proechimys is the most diverse genus in family Echimyidae, comprising 25 species (two of which are polytypic) and 39 taxa. Despite the numerous forms of this rodent and their abundance in nature, there are many t...

    Authors: Paulo JS Amaral, Cleusa Y Nagamachi, Renata CR Noronha, Marlyson JR Costa, Adenilson L Pereira, Rogerio V Rossi, Ana C Mendes-Oliveira and Julio C Pieczarka

    Citation: BMC Genetics 2013 14:21

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  42. Content type: Research article

    Sex chromosomes are subject to evolutionary pressures distinct from the remainder of the genome, shaping their structure and sequence content. We are interested in the sex chromosomes of domestic pigs (Sus scrofa

    Authors: Benjamin M Skinner, Kim Lachani, Carole A Sargent and Nabeel A Affara

    Citation: BMC Genetics 2013 14:3

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  43. Content type: Research article

    The karyotypes of Leptodactylus species usually consist of 22 bi-armed chromosomes, but morphological variations in some chromosomes and even differences in the 2n have been reported. To better understand the mec...

    Authors: Thiago Gazoni, Simone L Gruber, Ana PZ Silva, Olivia GS Araújo, Hideki Narimatsu, Christine Strüssmann, Célio FB Haddad and Sanae Kasahara

    Citation: BMC Genetics 2012 13:109

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  44. Content type: Research article

    To contribute to the knowledge of coleopteran cytogenetics, especially with respect to the genomic content of B chromosomes, we analyzed the composition and organization of repetitive DNA sequences in the Coproph...

    Authors: Sarah Gomes de Oliveira, Rita Cassia de Moura and Cesar Martins

    Citation: BMC Genetics 2012 13:96

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  45. Content type: Research article

    Squalius alburnoides is an Iberian cyprinid fish resulting from an interspecific hybridisation between Squalius pyrenaicus females (P genome) and males of an unknown Anaecypris hispanica- like species (A genome)....

    Authors: Isa Matos, Élio Sucena, Miguel P Machado, Rui Gardner, Ângela Inácio, Manfred Schartl and Maria M Coelho

    Citation: BMC Genetics 2011 12:101

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  46. Content type: Research article

    The accumulation of repetitive sequences such as microsatellites during the differentiation of sex chromosomes has not been studied in most squamate reptiles (lizards, amphisbaenians and snakes), a group which...

    Authors: Martina Pokorná, Lukáš Kratochvíl and Eduard Kejnovský

    Citation: BMC Genetics 2011 12:90

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